AMAarchives of neurology & psychiatry . - pale and showed marked chromatolysis. 164 IRC/IirES OF XEUROLOGY AXD PSYCHIATRY In s(jnic instances the tran>iti(in zone was not ])ronounce(l but, withspecial stains (scarlet red, Alzheimer-Mann), it could be demonstratedas a narrow space filled with gitter cells, proliferated glia and. in someinstances, cancer cells. The transition zone may thus Ije regarded as an area in process ofinvasion by the tumor mass spreading by direct jienetration, the tissuesbecoming so damaged as to offer little resistance. The demarcationzone, on the other hand, consis
AMAarchives of neurology & psychiatry . - pale and showed marked chromatolysis. 164 IRC/IirES OF XEUROLOGY AXD PSYCHIATRY In s(jnic instances the tran>iti(in zone was not ])ronounce(l but, withspecial stains (scarlet red, Alzheimer-Mann), it could be demonstratedas a narrow space filled with gitter cells, proliferated glia and. in someinstances, cancer cells. The transition zone may thus Ije regarded as an area in process ofinvasion by the tumor mass spreading by direct jienetration, the tissuesbecoming so damaged as to offer little resistance. The demarcationzone, on the other hand, consisted of more vigorous elements which. Fig. 8.—An area outside the demarcation zone. The glia reticulum is marked ;a blood vessel in the center shows a greatly rarefied brain tissue containinglymphocytes, plasma cells and gitter cells and is surrounded by a ring ofsyncytial glia. Bielschowsky stain counterstained with .-Mzheimer-Mann ; X 170. afforded some protection but yet, as will be seen, failed to save therest of the brain from damage. Separated, at times even remotely, from tliC main tumor mass werenumerous microsco])ic feci of cancer cells (Fig. 7). Such foci con-sisted of a small blood \essel, infiltrated or occluded by large tumorcells, with nuclei very rich in chromatin and provided with a welldeveloped membrane. Sometimes the cells were confined to the Xirchow- HASSIX-SIXGER—CEREBRAL CARCIXOMA 165 Robin spaces, but often tbey had broken through and, by proliferation,formed a larger focus. Then no trace of blood vessel could be detected,and the reactive and other phenomena approximated those of the maingrowth
Size: 1583px × 1579px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1910, bookpublisherchica, bookyear1919
