Twentieth century practice; an international encyclopedia of modern medical science by leading authorities of Europe and America . glands; this he designated as lymphaticleukaemia or lymphaemia, the same form being sj^oken of as small-celled (HeinzeUiche) leukaemia by Kottmann. The second form ischaracterized by the greater proportion of cells of large size such ashave been discovered in the spleen, and this variety was thereforecalled lienal leukaemia or spleuaemia by Virchow and large-celled(gwsszelUche) leukaemia by Kottmann. Later the investigations ofMosler, Neumann, and others made it cl
Twentieth century practice; an international encyclopedia of modern medical science by leading authorities of Europe and America . glands; this he designated as lymphaticleukaemia or lymphaemia, the same form being sj^oken of as small-celled (HeinzeUiche) leukaemia by Kottmann. The second form ischaracterized by the greater proportion of cells of large size such ashave been discovered in the spleen, and this variety was thereforecalled lienal leukaemia or spleuaemia by Virchow and large-celled(gwsszelUche) leukaemia by Kottmann. Later the investigations ofMosler, Neumann, and others made it clear that invohement of thebone marrow is important in certain cases, and the existence of med-ullary or myelogenic leukaemia was thus established. At the present 416 STENGEL—DISEASES OF THE BLOOD. time it is generally acknowledged that cases of leuksemia rarely involveone only of the blood-making structures, coincident disease of two ormore being the rule. The most frequent variety, as has alreadybeen indicated, is the combined splenic and myelogenous (the lieno-medullary form). Next in frequency are the cases in which the. Fig. 39. -Lymphatic Leukaemia; Lymphsemia. Showing excessive numbers of small mononuclearleucocytes or lymphocytes. lymphatic glands are involved to the exclusion, or at least to thepractical exclusion, of the spleen and bone marrow. For practicalpurposes these two varieties, the lienomedullary and the lymphatic,may be admitted as representing the important pathological varieties,and the condition of the blood serves to establish the existence of theone or the other with more or less certainty. It will be well now toconsider the individual forms of leucocytes as they are met with inthis disease. In this consideration the classification of Ehrlich isfollowed. Lympliocytes.—These forms are small mononuclear leucocytes, LEUKJiMIA. 417 having a nucleus rich iu cliromatiu and which therefore stains in-tensely with the nuclear staius. The size is usually less
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Keywords: ., bookcentury1800, bookdecade189, booksubjectmedicine, bookyear1895
