. Pathological technique; a practical manual for workers in pathological histology and bacteriology. lpus-formation. Intravenous or intraperitoneal inoculationof rabbits may also produce septicemia and death. PATHOGENIC BACTERIA AND FUNGI. 279 At autopsy the micrococci, arranged in tetrads, are foundin the blood generally, but most numerously in the can readily be demonstrated by cover-glass prepara-tions. Occurrence.— Found not infrequently in phthisical cavi-ties and sputum, occasionally in association with pyogeniccocci in abscesses connected with carious teeth and aboutthe neck
. Pathological technique; a practical manual for workers in pathological histology and bacteriology. lpus-formation. Intravenous or intraperitoneal inoculationof rabbits may also produce septicemia and death. PATHOGENIC BACTERIA AND FUNGI. 279 At autopsy the micrococci, arranged in tetrads, are foundin the blood generally, but most numerously in the can readily be demonstrated by cover-glass prepara-tions. Occurrence.— Found not infrequently in phthisical cavi-ties and sputum, occasionally in association with pyogeniccocci in abscesses connected with carious teeth and aboutthe neck and jaws and middle ear, rarely in abscesses else-where. It has been considered to be non-pathogenic forman, but it has been found in pure culture in closed ab-scesses in man, and Viquerst has proved experimentallythat it is capable of causing suppuration in human beings (Welch). Diplococcus Intracellulars Meningitidis.—Mor-phology,—Diplococci, occurring as paired hemispheres,separated by a well-marked unstained interval and showingconsiderable variation in size in cultures (Fig. 53). The. larger forms are regarded as involution or degenerate organism shows a tendency to grouping in fours ortetrads. In cover-glass preparations from the meningeal exudatethe diplococcus frequently is situated inside leucocytes, andsometimes within the nucleus (Fig. 54). The appearancesare very much like those of gonorrheal pus. It is decolor-ized by Grams method. Blood-serum.—The colonies appear after about twenty-fourhours, and after forty-eight hours may attain a diameter of 28o PATHOLOGICAL TECHNIQUE. 2 or 3 mm. They are round, colorless, shining, slightlyconvex or flat, moist, and viscid-looking. They may be-come confluent. Agar-agar.—Round, flat, grayish, translucent, moist, shin-ing colonies, attaining a diameter of 2 or 3 mm. after twenty-four hours in the incubator. They may become confluent,and in a slant culture the growth appears as a grayish,translucent, moist, sh
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