The problem of age, growth, and death; a study of cytomorphosis, based on lectures at the Lowell Institute, March 1907 . Fig. 23. Group of Five Nerve CellsFROM THE First Cervical Ganglion of aChild at Birth. Specimen preserved withosmic acid. X 500 diams.—After C. number of ways. Very frequently it comes aboutthat the alteration in the structure of the cell goes sofar in adapting it to a special function that it is un-able to maintain itself in good physiological condition,and failing to keep up its own nourishment it under-goes a gradual shrinkage which we call atrophy. Avery good il
The problem of age, growth, and death; a study of cytomorphosis, based on lectures at the Lowell Institute, March 1907 . Fig. 23. Group of Five Nerve CellsFROM THE First Cervical Ganglion of aChild at Birth. Specimen preserved withosmic acid. X 500 diams.—After C. number of ways. Very frequently it comes aboutthat the alteration in the structure of the cell goes sofar in adapting it to a special function that it is un-able to maintain itself in good physiological condition,and failing to keep up its own nourishment it under-goes a gradual shrinkage which we call atrophy. Avery good illustration of this, and a most important THE CELLULAR CHANGES OF AGE 69 one, is offered us by the changes which go on in thenerve cells in extreme old age. This is beautifullyillustrated by the two pictures which are now before. Fig, 24. Group of Four Nerve Cells from theFirst Cervical Ganglion of a Man Dying of OldAge at Ninety-two Years. Specimen preserved withosmic acid. C, C, two cells still intact, but loaded withpigment granules ; c, c, two cells which have disinte-grated. X 500 diams.—After C. F. Hodge. us, copied from investigations^ of Professor Hodge,of Clark University. The two figures representhuman nerve cells taken from the root of a spinal C. F. Hodge, Changes in Ganglion Cells from Birth to Senile Death,J our 7ial of Physiol.^ vol. xvii., pp. 129-134. 70 AGE, GROWTH, AND DEATH nerve. The first figure shows these cells as theyexist in their first maturity; the second figure,as they appear in a person of extreme old the latter you will readily notice that the cells, C,have shrunk and no longer fill the spaces allotted tothem, the nuclei have become small, and have losttheir conspicuous granules, and the protoplasm haschanged its appearance very strikingly because therehave been deposite
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