. A practical treatise on diseases of the skin, for the use of students and practitioners . This process is also coarsely appre-ciable, either by the free ooze of serum from the surface; or bythe imprisonment of such exuded fluid in the chambers of thevesicles which it produces; or by an increased thickening of thevarious constituents of the skin, perceptible when these arepinched up between the finger and thumb; or, lastly, by the ECZEMA. 115 appearance of various solid or semi-solid projections concerningthe skin proper, or, secondarily, its glandular appendages, whichvisibly spring from the
. A practical treatise on diseases of the skin, for the use of students and practitioners . This process is also coarsely appre-ciable, either by the free ooze of serum from the surface; or bythe imprisonment of such exuded fluid in the chambers of thevesicles which it produces; or by an increased thickening of thevarious constituents of the skin, perceptible when these arepinched up between the finger and thumb; or, lastly, by the ECZEMA. 115 appearance of various solid or semi-solid projections concerningthe skin proper, or, secondarily, its glandular appendages, whichvisibly spring from the involved area. Thus are explained thevarious erythematous, vesicular, pustular, and papular manifes-tations of eczema. A history of the many doctrines which have been held regard-ing the part played in these phenomena by the bloodvessels, thenerves, and the tissues would simply exhibit the several stepswhich have been taken in arriving at the facts now demonstra-ble. The researches of Heitzmann serve to throw light upon thisinflammatory process in the skin in a highly satisfactory • - <<*&» Chronic eczema—vertical section of the skin of the forearm, a, epidermis ; 5, thickened rete;e, hyper-pigmented layer of rete ; d, enlarged papilla;; e, atrophied sebaceous gland ; /, atro-phied hair follicle ; g, infiltrated corium. (After Kaposi.) As to the part played by the epithelium, Heitzmann1 showsthat the initial step of the inflammation is declared by an in-crease of the living matter, both within and between the proto-plasmic bodies; the former produces a coarse granulation of theepithelia due to increase of living matter. This increase is evi-dently due to augmented afflux of nutritive material in thestage of hypersemia. It is declared at the points of intersectionof the protoplasmic network (the formerly so called granules)by their enlargement, and by the shining and solid condition of 1 Transactions Arner. Derm. Association, Fourth Annual Meeting. 116
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