Interstate medical journal . e spindle cell production sufficient in Kruken-bergs opinion to justify a diagnosis of fibro-sarcoma. Other areasassumed a myxomatous appearance. Large epithelial cells appearedin groups scattered here and there, some of which were arranged indefinite tubules. These cells were described as being distended withmucoid material, which, after pushing the nucleus to one side,caused them to present a signet ring appearance. Stone, in 1916, emphasized the importance of the problems con-cerning the various routes of cancer metastasis. More particularlywas this brought out
Interstate medical journal . e spindle cell production sufficient in Kruken-bergs opinion to justify a diagnosis of fibro-sarcoma. Other areasassumed a myxomatous appearance. Large epithelial cells appearedin groups scattered here and there, some of which were arranged indefinite tubules. These cells were described as being distended withmucoid material, which, after pushing the nucleus to one side,caused them to present a signet ring appearance. Stone, in 1916, emphasized the importance of the problems con-cerning the various routes of cancer metastasis. More particularlywas this brought out in relation to the possible channels by whichsecondary growths make their appearance in the ovary. He con-cluded that chance distribution into the ovaries by way of the blood Reel: Krukenberg Cancer of the Ovary 521 or lymph system is but rarely encountered, but that metastasiseither occurs by a direct extension through the retroperitoneallymph nodes by permeation or retrograde transportation, or by peri-toneal Pig. 1.—From an area showing a distinctly carcinomatous type of growth.
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Keywords: ., bookcentury1900, bookdecade1910, bookidinter, booksubjectmedicine