. The Journal of nervous and mental disease. Death occurred February 14, 1914, about three years and a half afterthe trouble in the left hand was first noticed. Anatomical Examination.—Dr. Beerman performed the autopsyunder very inconvenient circumstances; what he brought away waspreserved in formaldehyde. It was about two years later that I firstinspected the material, and found the brain, which was uncut, thespinal cord, of which the lower end and most of the cervical part was ,oo L. NEWMARK missing, the spleen, a kidney, a small piece of the liver, and a bit ofa rib. No enlarged glands had
. The Journal of nervous and mental disease. Death occurred February 14, 1914, about three years and a half afterthe trouble in the left hand was first noticed. Anatomical Examination.—Dr. Beerman performed the autopsyunder very inconvenient circumstances; what he brought away waspreserved in formaldehyde. It was about two years later that I firstinspected the material, and found the brain, which was uncut, thespinal cord, of which the lower end and most of the cervical part was ,oo L. NEWMARK missing, the spleen, a kidney, a small piece of the liver, and a bit ofa rib. No enlarged glands had been seen at the autopsy. The piamater, it is said, appeared in the fresh state as if there had been asevere purulent meningitis, an impression caused by the leukemic condition. The spleen, after the long immersion, was not larger than a nor-mal organ. In it. as well as in the kidney, the rib and the liver therewas found on microscopic examination an intense lymphocytic infil-tration. In view of the concurrence which has been described of. Fig. i. Coronal section passing through optic nerves. Rsmaller than left. rht putamen slightly remarkable changes in the liver with disease of the lenticular nucleusit should be emphasized, perhaps, that no other affection was foundin the piece of liver than the foci of lymphocytes. The pia mater could be stripped from the brain without the brain in the coronal plane, passing throughthe lenticular nuclei, disclosed a marked difference in size betweenthem, the right appearing much shrunken. Large block- of tissue were kept in bichromate of potassium forral months; this necessitated dependence chiefly on Weigerts • LESION IN THE PUTAMEN 101 stain for myelin and on the Van Gieson mixture in preparing thatpart of the material for examination with the microscope. Microscopical Examination.—There is a general arterio-sclerosisthroughout the meninges, of long standing and of high degree, densefibrous thickening of the
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