. The elements of pathological histology with special reference to practical methods . epitheliumcovering the mucous membrane, as the case may be, and the outermostlayer of the cones very often consists of cylindrical cells (Fig. 48, a),similar to those in the lowest stratum of the original the cones grow rapidly in width, the cells lying in the centreare compelled from w^ant of space to take up a position on theiredges, and then, ranging themselves concentrically about a few cellswhich have retained their rounded form, they become flattened, andfinally cornify. In this manner
. The elements of pathological histology with special reference to practical methods . epitheliumcovering the mucous membrane, as the case may be, and the outermostlayer of the cones very often consists of cylindrical cells (Fig. 48, a),similar to those in the lowest stratum of the original the cones grow rapidly in width, the cells lying in the centreare compelled from w^ant of space to take up a position on theiredges, and then, ranging themselves concentrically about a few cellswhich have retained their rounded form, they become flattened, andfinally cornify. In this manner are formed the so-called pearls (cjn-dermic or cancroid glohnlcs), which even under a low power aredifferentiated from the surrounding parts by their yellowish colour(Fig. 48, c). If lateral pressure be made upon the cut surface of a fresh epithelioma,white plugs resembling comedones are forced out, which consist of 104 TUMOURS OR NEW-FORMATIONS the cancer-cell cones squeezed out from their places, and which appeardrier the larger the numher of cancer cells which have become Fig. 48.—Cone of Cancer-cells in an Epithklial 200. (Hfematoxylin and eosin.) a, Short cylindrical cancercells at the circumference of the cone ; 6, Spiny cells ; c, Concen-trically stratified epidermic globule. In some epitheliomata (those occurring on the vaginal portion of theuterus and in the urinary bladder) the stroma grows out into vascularpapillary structures, giving rise to the villous or papillary carcinoma(Fig. 49). (h) The Glandular Carcinoma or Adenocarcinoma.—This occurs inmucous membranes covered with cylinder-celled epithelium and in trueglands, and always begins as a growth of the glandular epithelium—inmucous membranes perhaps also of the surface epithelium—(, a), thus forming structures which at the beginning retain acertain resemblance to the glands from which they started, recallingthe appearance of acini and tubules (Fig. 50, & ; Fig. 130, h\ andFig. 1
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895
