. The principles of bacteriology: a practical manual for students and physicians. n eighty-six difierent occasions. Itsfirst appearance in this country was in Massachusetts in 1 For the literature on pathogenic streptothrices, see Flexner:Journal of Experimental Medicine, 1898, vol. iii. p. 435; for a sum-mary of cases in which streptothrices have been found, see Muaser,Pearce, and Gwyn: Transactions of the Association of AmericanPhysicijms, 1901, vol, xvi. p. 208, 372 BACTERIOLOGY. 1627; since that time there have been twenty-two vis-itations of influenza to the United States. The pan-demic o


. The principles of bacteriology: a practical manual for students and physicians. n eighty-six difierent occasions. Itsfirst appearance in this country was in Massachusetts in 1 For the literature on pathogenic streptothrices, see Flexner:Journal of Experimental Medicine, 1898, vol. iii. p. 435; for a sum-mary of cases in which streptothrices have been found, see Muaser,Pearce, and Gwyn: Transactions of the Association of AmericanPhysicijms, 1901, vol, xvi. p. 208, 372 BACTERIOLOGY. 1627; since that time there have been twenty-two vis-itations of influenza to the United States. The pan-demic of 1889-90, the most severe for a long time,appears to have originated in Central Asia and to havespread pretty much over the entire civilized world. Theadvent of influenza in a community is always remark-able for its astonishing rate of transmission from per-son to person and its dissemination over wide areas. During the recent pandemic investigations havingfor their object the discovery of its cause Avere insti-tuted, with the result of demonstrating in the catarrhal Fig. Bacillus of influenza in sputum. secretions from the air-passages a micro-organism thatis claimed to stand in causal relation to influenza. This organism, baoillus influenzce, as it is called, wasdiscovered, isolated, cultivated, and described by It is a very small, slender, non-spore-foi-ming, non- Tim BACILLUS OF IXFLUENZA. 373 motile, aerobic bacillus, occurring singly and in pairs,joined end to end. It stains with watery solutions ofthe ordinary basic aniline dyes; somewhat better -w-ithalkaline methylene-blue, but best when treated for fiveminutes with a dilution of Ziehls carbol-fuchsiu inwater (the color of the solution should be pale red).(Fig. 66.) It is decolorized by the method of Gram. It develops only at temperatures ranging from 26°to 43° C. Its optimum temperature for growtli is37° C. It possesses the peculiarity of developing upononly those artificial culture-media to which


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