. The American journal of roentgenology, radium therapy and nuclear medicine . thiscondition such a criterion can be deceptive. Progressive destruction by chronic pul-monary tuberculosis consists in an increaseand a coalescence of the mottling, advanc-ing usually from apex toward base andfrom periphery toward hilum. Increasingdensity implies caseation with or withoutfibrosis, and in chronic progressive diseaseit is usually only a question of time untilthe dense shadows of caseation acquire amoth-eaten appearance implying beginningcavitation. These small areas of rarefactiongradually merge with


. The American journal of roentgenology, radium therapy and nuclear medicine . thiscondition such a criterion can be deceptive. Progressive destruction by chronic pul-monary tuberculosis consists in an increaseand a coalescence of the mottling, advanc-ing usually from apex toward base andfrom periphery toward hilum. Increasingdensity implies caseation with or withoutfibrosis, and in chronic progressive diseaseit is usually only a question of time untilthe dense shadows of caseation acquire amoth-eaten appearance implying beginningcavitation. These small areas of rarefactiongradually merge with one another, forming-one or more large cavities. The older thecavity, the cleaner and less ragged it looks,and the more likely it is to assume the formof a sphere or a closely allied geometricalfigure. Rarefaction typically begins in anupper lobe near the periphery and, likemottling, advances downward and ma\ be slow, when it is almostal\\a\s associated with progressive fibrosis, Serial Roentgenographic Observations of Chronic Pul monary Tuberculosis 641. I. Time interval between (a) Heavy infiltration, mosthsymptoms of active tuberculosis, and b, 5 months: between b and c, months; between c and d, ; total, in lower half of right lung; lighter infiltration on left. Patient hadincluding fever; sputum, 136 grams daily; numerous tubercle bacilli present.(6) Process more marked in both lungs with possibility of small pleural effusion on right. Between a and bsymptoms of activity persisted with gradually lessening severity; tubercle bacilli still present in sputum, (c)Clearing of mottling with pleural thickening and beginning fibrosis on right. Symptoms between b and cimproved uninterruptedly; sputum scant; tubercle bacilli disappeared from sputum two months before roent-genogram c was made, (d) Continued anatomical repair; remarkable clearing with restoration of definitehilum outline and only a few residual deposits in the lun


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