. Tumours, innocent and malignant; their clinical characters and appropriate treatment. euterine cavity is filled with villi (Fig. 177). Each of thesehas a delicate axis of vascular connective tissue coveredwith a single layer of columnar epithelium. The clinicalsigns are similar to those caused by cancer of the corporealendometrium. Adeno-myoma.—This term is applied to a pathologic con-dition of the uterus the leading features of which have beenadmirably summarized by Cullen in the following terms: It is diffuse in character, situated in the middle layer of 376 EPITHELIAL TUMOURS the uterine
. Tumours, innocent and malignant; their clinical characters and appropriate treatment. euterine cavity is filled with villi (Fig. 177). Each of thesehas a delicate axis of vascular connective tissue coveredwith a single layer of columnar epithelium. The clinicalsigns are similar to those caused by cancer of the corporealendometrium. Adeno-myoma.—This term is applied to a pathologic con-dition of the uterus the leading features of which have beenadmirably summarized by Cullen in the following terms: It is diffuse in character, situated in the middle layer of 376 EPITHELIAL TUMOURS the uterine wall, and is dependent on the uterine mucosafor its glandular elements. Although several observers, in-cluding von Recklinghausen, have recorded isolated examplesof this disease, Cullen seems to have been the first to drawattention to its clinical importance (1897). In well-marked cases adeno-myoma presents clinicalfeatures which cause it to resemble the common varietiesof submucous fibroids. The ages of the patients varyfrom 20 to 50 years ; the uterus is usually enlarged, but in. Fig. 179.—Microscopic features of diffuse adeno-myoma of the uterus. X 60.{Frraik E. Taylor.) exceptional instances adeno-myoma occurs in small atrophicuteri. Adeno-myomatous changes are often associated withfibroids. Small bodies under the serous coat of these uterioften resemble stalked subserous fibroids; they are really buds of adeno-myomatous tissue. When the uterus is removed and divided longitudinally,the walls are seen to be greatly thickened, measuring in somespecimens 5 cm. (2 in.) in thickness ; this increase is dueto the formation of new tissue between the outer wall of theuterus (the subserous stratum) and the superficial layer ofthe endometrium. There is no attempt at encapsulation,and the term diffuse is thoroughly justified. (Fig. 178.) ADENO-MYOMA OF TEE UTERUS 377 The cut surface of the adventitious tissue differs from thatpresented by the common hard fibroid in another particul
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectneoplasms, bookyear19
