A treatise on the diseases of the nervous system . isease, occupying the sub-occip-ital region. They are generally quite constant, but are more violentat some times than at others. They extend to the joints, which, how-ever, are not ordinarily the seat of swelling, and with these pains thereare the various sensations of numbness in the superior extremities, andsome degree of paralysis. Sometimes there are bulbous and pemphi-goid eruptions. The second period is characterized by other symptoms, which appearto be due to the extension of the meningeal lesion to the spinal cord,and to a more profou
A treatise on the diseases of the nervous system . isease, occupying the sub-occip-ital region. They are generally quite constant, but are more violentat some times than at others. They extend to the joints, which, how-ever, are not ordinarily the seat of swelling, and with these pains thereare the various sensations of numbness in the superior extremities, andsome degree of paralysis. Sometimes there are bulbous and pemphi-goid eruptions. The second period is characterized by other symptoms, which appearto be due to the extension of the meningeal lesion to the spinal cord,and to a more profound alteration of the peripheric nerves. The limbs cease to be painful, but they become paralyzed, and themuscles are atrophied, and the atrophy extends to all the muscles ofthe extremity. But, speaking only of the muscles of the arm and fore-arm, it is notable that those which receive their innervation from theulnar* and median nerve are especially affected, while those which aresupplied by the radial nerve almost entirely escape. From this pecu-. Fig. 36. liarity a certain character of deformity results, which, though met within other diseases, and not always seen in the affection under notice, is,nevertheless, not a feature of other forms of muscular atrophy. It is,consequently, a diagnostic mark of some value (Fig. 36). To these 1 M. Charcot says, du nerf radial et du nerf median, but it is evident from the con-text, as well as from what follows, that radial is a misprint for cubital (op. cit., p. 251).The cut also shows the error. 44G DISEASES OF THE SPINAL CORD. symptoms are added contractions, and often anaesthesia, which may ex-tend from the extremities to the trunk. After a while, the inferiorextremities become paralyzed, and eventually contractions ensue inthem also. Charcot does not regard hypertrophic pachymeningitis as a neces-sarily incurable affection: for a woman, who, for five or six years, ex-hibited all its characteristic symptoms, being confined to her bed fo
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