Clinical electrocardiography . cellular, and (2) the increased cardiacwork accompanying the elevation of the basal metabolic rate. Electrocardiograms of patients with exophthalmic goiter () or with adenoma with hyperthyroidism are modified largelyby the degree of myocardial degeneration. Auricular fibrillationis a very frequent phenomenon, often disappearing after thyroid-ectomy when the basal metabolic rate attains normal. ELECTROCARDIOGRAPHIC STUDY OF HEART DISEASE 157 Myxedema.—Electrocardiograms of patients with myxedemausually reveal deflections of low amplitude, particularly of th


Clinical electrocardiography . cellular, and (2) the increased cardiacwork accompanying the elevation of the basal metabolic rate. Electrocardiograms of patients with exophthalmic goiter () or with adenoma with hyperthyroidism are modified largelyby the degree of myocardial degeneration. Auricular fibrillationis a very frequent phenomenon, often disappearing after thyroid-ectomy when the basal metabolic rate attains normal. ELECTROCARDIOGRAPHIC STUDY OF HEART DISEASE 157 Myxedema.—Electrocardiograms of patients with myxedemausually reveal deflections of low amplitude, particularly of the Twave. Figure 138 is the electrocardiogram of a patient sufferingfrom high-grade myxedema. Note the low amplitude T wave in Derivation III is negative. Angina Pectoris.—Angina pectoris does not produce character-istic electrocardiograms, although group study reveals certain ab-normalities which occur quite constantly. Data in a series of 155cases of angina pectoris recently published showed that coronary. Fig. 138.—Electrocardiogram of a patient with high-grade myxedema. disease occurred in per cent, of cases, aortic disease in percent., and mitral stenosis in per cent. Thirty electrocardiograms ( per cent.), including ventricularpreponderance and T wave negativity in Derivation III, wereconsidered normal. Changes in the Final Ventricular T Wave.—Abrupt peakedpositive T waves of exaggerated amplitude occurred in percent, of the electrocardiograms. T wave negativity occurringin isolated and combined derivations was present in per cent,of the electrocardiograms. No significance can be attached to 158 CLINICAL ELECTROCARDIOGRAPHY T wave negativity in Derivation III alone, as it occurs in normaland in diseased hearts. Excluding T wave negativity in Deriva-tion III, 51 patients ( per cent.) had significant T wave nega-tivity. T wave negativity in Derivation I occurred in 25 ( percent.) electrocardiograms, in combined Deri


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