. The clinical study of blood-pressure : a guide to the use of the sphygmomanometer in medical, surgical, and obstetrical practice, with a summary of the experimental and clinical facts relating to the blood-pressure in health and in disease . to feed a dog enormous quantities of bouillon without anyrise in pressure. In such experiments, part of the excess vol- Tappeiner. Bericht der sachs. Gesellsch. der Wissensch., math. , 1872, pp. 199 and following. Quoted by Tigerstedt, Lehrbuch, p. 345. Langley. Philosophical Transactions, 1889, vol. clxxx B, p. 138. Quotedby Tigerstedt, Lehrb


. The clinical study of blood-pressure : a guide to the use of the sphygmomanometer in medical, surgical, and obstetrical practice, with a summary of the experimental and clinical facts relating to the blood-pressure in health and in disease . to feed a dog enormous quantities of bouillon without anyrise in pressure. In such experiments, part of the excess vol- Tappeiner. Bericht der sachs. Gesellsch. der Wissensch., math. , 1872, pp. 199 and following. Quoted by Tigerstedt, Lehrbuch, p. 345. Langley. Philosophical Transactions, 1889, vol. clxxx B, p. 138. Quotedby Tigerstedt, Lehrbuch, p. 350. Worm-Miiller. Bericht der sSch. Gesellsch. der Wissensch., math. , 1873, pp. 573-664. Quoted by Tigerstedt, Lehrbuch, p. 345. * Pawlow, Joh. Zur Lehre iiber die Innervation der Blutbahn. Arch. i. Physiologie d. Menschen u. d. Thiere, 1879, vol. xx, pp. 33, 34. FACTORS DETERMINING BLOOD-PRESSURE 27 ume is removed from the circulation by the secreting organs,especially the kidney, and part by increased transudation intothe lymph spaces and serous cavities ; the remainder is accom-modated by the vessels, which dilate, either through a directvascular reflex, or in response to a reflex from the heart by the. Fig. 6.—Fall in blood-peessdre pkoduoed by u^ from rabbits carotid. Slow drum. depressor nerve. Under certain circumstances, such as toorapid infusion, the heart may empty itself less completely(Johannson and Tigerstedt).* Johannson, J. E., und Tigerstedt, Robert. TJeber die gegenseitigen Bezieh-ungen des Herzens und der Gefasse. Skandinavisches Arch. f. Physiol., 1889,vol. i, p. 397, 28 BLOOD-PRESSURE IN THE NORMAL ANIMAL Therefore, within certain wide limits, thevolume of circulating blood has, in the normalanimal, only a subordinate and temporary in-fluence on mean blood-pressure. It is evident that the regulating influences, which preventexcessive increase of the quantity of circulating fluid, will notbe operative when that qu


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