Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . in color; themiddle stratum is aclear serous fluid, butslightly tinted; the sed-iment is greenish-brown,occasionally pus-like,and contains the char-acteristic odor in itsfullest fibers are notalways present, al-though they usually areto be found; Eijkman^has shown that certainbacteria evolve an elas-tica-dissolving enzyme, and it is possible that the disappearance of elastictissue in pulmonary gangrene may be attributable to the action of somesuch substance. The


Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . in color; themiddle stratum is aclear serous fluid, butslightly tinted; the sed-iment is greenish-brown,occasionally pus-like,and contains the char-acteristic odor in itsfullest fibers are notalways present, al-though they usually areto be found; Eijkman^has shown that certainbacteria evolve an elas-tica-dissolving enzyme, and it is possible that the disappearance of elastictissue in pulmonary gangrene may be attributable to the action of somesuch substance. The color of the diseased tissue is dependent upon thestage and, probably to a large extent, upon the character of the , it is brown or reddish brown; and later, quite black. The color-changes are in part brought about by the presence of blood pigment, towhich the brownish hue is to be attributed. The blackening is partlydue to changes in the hemal iron as well as to the presence of iron-freepigment. The occasional greenish hue, which may be marked, is1 Centralbl. f. Bakt., Nov. 5, 1903, p. Fig. 294.—Part of Right Lung, Circumscribed Two pockets of gangrenous cavity. B. Dilated bronchus \^^th gan-grenous walls. C,C. Solidified zone of pulmonary Adhesion between superior and inferior lobes. E. Beginningabscess at margin of gangrenous area. Ol RFSPIkATKJN. 597 due to changes in normal pigments or to the i)resence of the bacilluspyocvaneus. In the earlier stages the gangrenous tissue may retainits structure, but disintegration rapidly ensues, and a cavity with raggedirregular walls forms, inclosing a green or reddish-yellow mass of soft-ened necrotic tissue. Passing into, often across, the cavity are remainsof blood-vessels and bronchi. By reason of the infectious characterof the lesion, the blood-vessels are not occluded, as normally, by anorganizing thrombus; the coagulum forming in the lumen being infected,is easily displaced


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