A reference handbook of the medical sciences, embracing the entire range of scientific and practical medicine and allied science . helial cells are trans-ferred through the lymph- and blood-vessels or tissuespaces, and give rise to new tumors which use thelocal connective tissue as a framework for their furtliergrowth. Without the presence of such a scaffoldingto carry nourishment to the epithelial cells, an ex-tensive growth of the carcinoma is impossible, thecentral portions of the solid epithelial masses under-going an early necrosis. The results of animal ex-periments have shown also that
A reference handbook of the medical sciences, embracing the entire range of scientific and practical medicine and allied science . helial cells are trans-ferred through the lymph- and blood-vessels or tissuespaces, and give rise to new tumors which use thelocal connective tissue as a framework for their furtliergrowth. Without the presence of such a scaffoldingto carry nourishment to the epithelial cells, an ex-tensive growth of the carcinoma is impossible, thecentral portions of the solid epithelial masses under-going an early necrosis. The results of animal ex-periments have shown also that the successful trans-plantation of carcinoma depends upon an early andactive reaction of the connective tissue in which thegraft is placed, with rapid vascularization of theengrafted fragment. In immune animals this stromareaction does not occur, and the epithelium of thegraft dies from lack of nutrition. In contrast to theextraordinary vitality of the cancer cell it should beremembered that normal epithelium does not possessthe power of indefinite transplantation, but soon dieswhen transferred from its natural Fig. 1192.—Beginning . Cell Epithelioma of SldnShowing Downgrowth of Tumor Cells and Pearl 100. While the growth of human carcinoma is unlimitedas compared to normal tissues, it is restricted bv theavailable space of the body and the length of life ofthe person bearing it, consequently it is only in thecareinomata of animals that this extraordinarycapacity of growth is to any extent realized. Inmice, for example, careinomata have been propagatedthroughout so long a period as ten years, and in manycases the tumor has weighed nearly as much as theanimal bearing it. Classification.—Careinomata are grouped ac-cording to the varieties of epithelium from which thevarise: 1. Squamous-ceU carcinoma (Fig. 1192), from thesquamous epithelium of the skin; 2. Basal-cell carcinoma (Fig. 1193), from theMalpighian layer or glands of the skin; 3.
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Keywords: ., bookauthorbuckalbe, bookcentury1900, bookdecade1910, bookyear1913
