Induced cell-reproduction and . Fig. 107.—Division in a leucocyte induced by kreatin. No stain or extract KREATIN AND XANTHIN 319 With atropine: Kreatin. gramme . . No mitosis. ... Mitosis. . . Well-advanced divisions. Employing xanthin the presence of atropine is necessary: Xanthin. gramme . . Early mitosis. If the jelly contained saturated solution1 of xanthin,well-marked figures were seen. We had now succeeded in inducing the reproductionof leucocytes and lymphocytes—first by the aniline dyeazur, then by a substance contained in the extractof suprarenal gland,
Induced cell-reproduction and . Fig. 107.—Division in a leucocyte induced by kreatin. No stain or extract KREATIN AND XANTHIN 319 With atropine: Kreatin. gramme . . No mitosis. ... Mitosis. . . Well-advanced divisions. Employing xanthin the presence of atropine is necessary: Xanthin. gramme . . Early mitosis. If the jelly contained saturated solution1 of xanthin,well-marked figures were seen. We had now succeeded in inducing the reproductionof leucocytes and lymphocytes—first by the aniline dyeazur, then by a substance contained in the extractof suprarenal gland, and by our experiments we wereable to infer that this substance is contained in theextracts of other dead tissues. It has just been shownthat this inference is correct, because cell-division canbe induced by the crystalline extractive kreatin, whichis a constituent of the remains of all dead tissues. Sofar, of course, we had only induced divisions with thesesubstances in vitro; but, as already pointed out, thecells are under
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