The pathology and surgical treatment of tumors . , and which seems to proceed to an extreme more often thanin any other equally emaciating and cachectic disease. There is, how-ever, reason to believe that in most cases of spontaneous fracture with-out tumor-formation, in which it was believed the fracture occurredwithout implication of the bone, the fracture was the result of thesecondary bone-carcinoma, which was overlooked, life not being suf-ficiently prolonged for the appearance of a swelling. In favor of thisview is the fact that pathological fractures under such circumstancesare seldom m
The pathology and surgical treatment of tumors . , and which seems to proceed to an extreme more often thanin any other equally emaciating and cachectic disease. There is, how-ever, reason to believe that in most cases of spontaneous fracture with-out tumor-formation, in which it was believed the fracture occurredwithout implication of the bone, the fracture was the result of thesecondary bone-carcinoma, which was overlooked, life not being suf-ficiently prolonged for the appearance of a swelling. In favor of thisview is the fact that pathological fractures under such circumstancesare seldom multiple, which would be the case if the marasmus of car-cinoma produced general atrophy of the bones. The carcinomatousmaterial is previously deposited in the Haversian canals, along which itinfiltrates the bone, producing enlargement of the canals. Miliary carcinosis very closely resembles miliary reported seven cases of miliary carcinosis, and, basing hisopinion regarding its etiology upon a study of the clinical history of. Fig. 137.—Carcinomatous capillary embolism of the choroid; X 320 (after Perls): b, capillary net dilatedand filled partly with red blood-corpuscles and partly with carcinoma-cells ; c, large nuclei. these cases, came to the conclusion that it is most frequently producedby trauma. The diffuse general dissemination of carcinoma is usuallyinitiated by a rise in temperature and by other febrile disturbances that 232 PATHOLOGY AND TREATMENT OF TUMORS. closely simulate the general symptoms which inaugurate and attendmiliary tuberculosis. In almost all organs of the body, and more par-ticularly upon the serous surfaces, innumerable nodules, from the sizeof a mustard-seed to that of a hempseed, appear. The nodules areproduced by capillary emboli composed of carcinoma-cells (Fig. 137).Miliary carcinosis is a rapidly fatal affection. It is probably producedmost frequently by perforation of a vein-wall by the primary or asecondary carcinoma, the
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectneoplas, bookyear1895
