. Comparative animal physiology. Physiology, Comparative; Physiology, Comparative. 588 Comparative Animal Physiology velocity (Ch. 23). At the end-plate a nerve impulse causes a local depolar- ization which is manifest as an end-plate potential ()- The may be associated with an increase in acetylcholine at the end-plate, either from the nerve endings^«' '''â '*' or from the muscle sole plate.^^-^^ The local end-plate potential is graded in size and spreads electrotonically for a few. Fig. 219. Action potentials trom the region of the end-plate in frog muscle: a, before curarizati


. Comparative animal physiology. Physiology, Comparative; Physiology, Comparative. 588 Comparative Animal Physiology velocity (Ch. 23). At the end-plate a nerve impulse causes a local depolar- ization which is manifest as an end-plate potential ()- The may be associated with an increase in acetylcholine at the end-plate, either from the nerve endings^«' '''â '*' or from the muscle sole plate.^^-^^ The local end-plate potential is graded in size and spreads electrotonically for a few. Fig. 219. Action potentials trom the region of the end-plate in frog muscle: a, before curarization; b to d, increasing degrees of curarization; e, curarization completeâ alone. AU-or-none propagated spike arises from in ad. From Kuffler.^^^ millimeters around the end-plate, where it sets off the muscle action poten- tial (Fig. 219). The can be detected only at or near the neuromuscu- lar junction, and under increasing curarization it becomes gradually re- duced (Fig. 219). When the end-plate potential is reduced by curare to below about 30 per cent of its maximum the muscle impulse can no longer be initiated.^'*'* With two or more nerve impulses the graded 's can. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Prosser, C. Ladd (Clifford Ladd), 1907-; Bishop, David W. Philadelphia, Saunders


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