. Cell heredity. Cytogenetics. 220 CELL HEREDITY. 34 68 135 270 540 IC X-ray Dose (r) 2160 4320 FIGURE Number of mef-2^ mutants induced in E. coli met-2~ by increasingly large doses of X-rays (after Demerec and Sams, in: Buzzati-Traverso, 1960, Immediafe and Low Level Effects of Ionizing Radiafions, p. 283, London, Taylor and Francis, Ltd.). tor mutation because for every aliquot of dose the same number of muta- tions are induced, according to the equation: M = kD (] where M is the number of induced mutants, k is some dose-independent constant describing the sensitivity of the tar
. Cell heredity. Cytogenetics. 220 CELL HEREDITY. 34 68 135 270 540 IC X-ray Dose (r) 2160 4320 FIGURE Number of mef-2^ mutants induced in E. coli met-2~ by increasingly large doses of X-rays (after Demerec and Sams, in: Buzzati-Traverso, 1960, Immediafe and Low Level Effects of Ionizing Radiafions, p. 283, London, Taylor and Francis, Ltd.). tor mutation because for every aliquot of dose the same number of muta- tions are induced, according to the equation: M = kD (] where M is the number of induced mutants, k is some dose-independent constant describing the sensitivity of the target, and D is the dose of radiation. Were two hits in one target or one hit in two targets re- quired, the curve would be exponential, the first dose yielding prepara- tory hits and later doses proportionately more hits within targets already hit once. That the whole cell is not the target particle is indicated by a calcula- tion of the target size. This is done on the assumption that a larger target would be hit more often than a smaller one by radiation which, like X-rays, is of known density and randomly distributed in space. It. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Sager, Ruth; Ryan, Francis J. (Francis Joseph), 1916-. New York, Wiley
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