British medical journal . entral blood clot the opsonizing effect of the li.]uor purison the red cells can be observed. If highly toxic, noemigration of leucocytes takes place, but if the liciuor purisis liealthy itliat is, from a well drained, healthy wound),numbers of cells will emigrate on to the slide, some willshow the iodophil reactiou, and some, generally in theperipheral zone, will be covered with clumped red cells,?while a certain number will have ingested some of the redcells which adhere to them iFig. IX). Thus, by the addition of a hacmagglutiniu to a liquorpuris or a serum, we can
British medical journal . entral blood clot the opsonizing effect of the li.]uor purison the red cells can be observed. If highly toxic, noemigration of leucocytes takes place, but if the liciuor purisis liealthy itliat is, from a well drained, healthy wound),numbers of cells will emigrate on to the slide, some willshow the iodophil reactiou, and some, generally in theperipheral zone, will be covered with clumped red cells,?while a certain number will have ingested some of the redcells which adhere to them iFig. IX). Thus, by the addition of a hacmagglutiniu to a liquorpuris or a serum, we can induce the leucocytes to phage-cytosc native red cells—that is, red cells from the sameblood—when incubated together. Iso-phagocytosis of red cells by pus cells may also be observed in pus from woundsiu patients whoso blood serum is haemagglutiuative. Tljus we arrive at this position. Ius cells from wholepus (it it contains haemagglutinins of the right kind) willingest washed human red cells more freely than washed. FiG. IS.—SbowiDg tlie pliogocytosis of (C J. B.) reJ cells byC. J. U. leucocytes iu a di-op of C. J. B. blood iLcubated in ag^lu-tiuatiujl liquor i> ris ; drop and i»ool** uielbod. (Drawing fromuiicrosooiJo slide.; 1. .Vtjglutiuated red cells; 2, red cells inBhagocyic. pus cells from the same pus will digest them, althoughthe wasliing iu .saline actually increases the activity of thecells by removing the bacterial toxins and tryptic contentof the liquor puris. The difference in the two casesdeiiends en the fact that haemagglutinins are present iuthe whole pus and absent in the washed cells. More-over, no ingestion of red cells occurs if tlie whole pusis nou-agglutiuative. Putting all these facts together, we must, I think, con-clude that, as far as the phagocytosis of red cells by leuco-cytes is concerned, haemagglutinins also act as opsoninsand prepare the red cells for The question remains as to the origin of the haemagglu-tinins in the bloo
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Keywords: ., bookcentury1800, bookdecade1850, booksubjectmedicine, bookyear185
