Carpenter's principles of human physiology . bjects not reduced by previous abstinence, being one that com-paratively seldom occurs. There is no doubt, however, of their normalpresence in the spleen of Man, as in that of other Mammalia.—Diffusedamidst the parenchyma of the spleen, but in very variable amount, areboth coloured and colourless cells, some of which are unchanged blood-corpuscles, whilst others appear to be transitional forms between leucocytesand red blood-cells.* Others, again, seem to be blood-discs in various stagesof retrograde metamorphosis; these gradually diminishing in siz
Carpenter's principles of human physiology . bjects not reduced by previous abstinence, being one that com-paratively seldom occurs. There is no doubt, however, of their normalpresence in the spleen of Man, as in that of other Mammalia.—Diffusedamidst the parenchyma of the spleen, but in very variable amount, areboth coloured and colourless cells, some of which are unchanged blood-corpuscles, whilst others appear to be transitional forms between leucocytesand red blood-cells.* Others, again, seem to be blood-discs in various stagesof retrograde metamorphosis; these gradually diminishing in size, andassuming a golden-yellow, brownish-red, or even blackish colour, or havingthe pigmentary matter crystallized in a rod-like form in their interior;or, again, breaking-up into detached pigment-granules. The colourlesscorpuscles are probably only nucleated buds of the general matrix, andafter separation are carried away in the blood-current as lymphoid cor-puscles.! Occasionally (though very rarely in the Human subject) little Fig. Malpighian corpuscle from the spleen of the Hedgehog, with itsvascular supply.—6, Splenic pulp, with the intermediary blood-passages; c, the rootlets of the veins. clusters of from 1 to 20 degenerating blood-corpuscles are found, includedin a vesicular envelope, j Some of these bodies are seen in the blood of theSplenic vein; and it has been hence concluded that they do not consti-tute normal elements of the Splenic parenchyma, but that they are eithercontained in its capillaries, or, if actually diffused through the pulp, are so as * On this point see Freyer, Inaug. Dissert. Konigsberg, 1874; and E. Neumann, Archivf. Heilkunde, Band xv. p. 441. + Klein, Quart. Journ. Mic. Science, vol. xv. p. See Gulliver, Lond. and Edin. Phil. Mag., 1842, p. 169, Fig. 2. P 210 OF ABSORPTION AND SANGUIFICATION. a result of an abnormal extravasation. The course of the blood through thespleen appears to be, as stated by Mr. Gray and W. Miiller, that
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