Diseases of the nervous system : a text-book of neurology and psychiatry . —Dercum first named one of these patients slowly develop fatty deposits, often enormous in adiposity may show as nodular deposits (symmetrical lipomatosis),varying in size from a bean to an apple. They may be circum-scribed or the adipose deposits may be generally diffused throughoutthe entire body. The hips, shoulders, upper arm and abdomen arepredilection sites. The skin is tense. The fatty deposits are painfulto pressure, especially at nodular points, and even at times beforethere
Diseases of the nervous system : a text-book of neurology and psychiatry . —Dercum first named one of these patients slowly develop fatty deposits, often enormous in adiposity may show as nodular deposits (symmetrical lipomatosis),varying in size from a bean to an apple. They may be circum-scribed or the adipose deposits may be generally diffused throughoutthe entire body. The hips, shoulders, upper arm and abdomen arepredilection sites. The skin is tense. The fatty deposits are painfulto pressure, especially at nodular points, and even at times beforethere is much fatty infiltration. Hyperesthesise and paresthesise inthe form of tingling, burning, numbness, etc., are frequent. Spon-taneous pains occur with some. They are sharp and intermittent,localized in the skin or more deeply, and often increase with is a marked sign and psychical alterations are the rule. Theselatter are mostly in the nature of depressions with, at times, suicidalideas, irritability, capriciousness and other signs closely resembling. Fig. 59.—Adiposis dolorosa. (Dercum.) manic-depressive states (q. v.) with flight of ideas and patients show marked deteriorations. Various anomalous conditions have been observed with differentpatients, such as vasomotor signs with edemas, ecchymoses, hemor-rhages, and pigmentation. Hyperidrosis, anidrosis, and trophic changesalso are recorded. Various complications with other members of thisvast collection of chemical metabolism anomalies are too numerous tomention. The disorders usually progress slowly and var}^ greatly in intensityfrom year to year. The patients recover spontaneously or finally dieof intercurrent disease. The organs involved have been the hypophysis and the thyroidchiefly, but the exact relationships are still uncertain. Hypophysealtumors are not infrequently found, ovarian disease is present in some,vascular neurotrophic disorders (blood gland disease) are present instil
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