. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . tly distendedwith blood. The liver is necrotic. In front of the head thetissue is broken away, leaving a pocket which contained thefore-brain. Above this the brain protrudes. The cord andfourth ventricle are distended and dissociated. The epidermisis intact. No. 344. Ovum, 45 x 45 x 45 mm.; embryo, , 16 mm. Professor Minot. The wall of the chorion is very thin, with a few fibrousvilli scattered over it. It contains no blood-vessels. Thelong thin umbilical co


. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . tly distendedwith blood. The liver is necrotic. In front of the head thetissue is broken away, leaving a pocket which contained thefore-brain. Above this the brain protrudes. The cord andfourth ventricle are distended and dissociated. The epidermisis intact. No. 344. Ovum, 45 x 45 x 45 mm.; embryo, , 16 mm. Professor Minot. The wall of the chorion is very thin, with a few fibrousvilli scattered over it. It contains no blood-vessels. Thelong thin umbilical cord is fibrous and shows remnants ofblood-vessels. The embryo has a rounded head and stumpy legs. Itstissues are dissociated, the brain being distended and macer- 334 MALL. [Vol. XIX. ated, too. The medulla has expanded towards the and blood-vessels are distended and in many places thewalls are destroyed and the blood cells extend into the sur-rounding tissues. This is very marked in the liver. The legsare filled with an even mass of round cells, i. c, the tissues aredissociated. Some of the epidermis has fallen Fig. 344.—Photograph of the embryo attached to the chorion. X 2 times. No. 345. Ovum, 60 x 50 x 50 mm.; embryo, 19 mm. Professor Minot. The fleshy ovum is composed largely of decidua, in whichare buried plugs of mucus, pus and necrotic villi of thechorion. The embryo is normal in shape. The tissues of the No. i.] ORIGIN OF HUMAN MONSTERS. 335 embryo are macerated, but on account of the distended me-dulla which encroaches upon the mouth I think it likely thatthe tissues were dissociated before they became macerated. No. 346. Embryo, C. R., 13 mm. Professor Minot. A piece of hemorrhagic chorion, which may have been 50mm. in diameter, is attached to the embryo. Its tissues aremacerated, but they are well enough preserved to show thatmuch mucus and pus are between some of the villi. The


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