Diseases of the nervous system : a text-book of neurology and psychiatry . e pituitary need-ing the thyroid to complete its activities. Hyperthyroid activitydoes not lead to hyperplasias of connective or bony tissues as doeshyperpituitary action; the reciprocal autonomic and sympatheticnerve activity is not exactly similar; although diminished activityof both substances may lead to diminished bony growth— vegetative mechanism of this, however, has not yet beenelucidated. The action of thymus on thyroid is far from clear, but the tendencyis to show a reciprocal checking action especi
Diseases of the nervous system : a text-book of neurology and psychiatry . e pituitary need-ing the thyroid to complete its activities. Hyperthyroid activitydoes not lead to hyperplasias of connective or bony tissues as doeshyperpituitary action; the reciprocal autonomic and sympatheticnerve activity is not exactly similar; although diminished activityof both substances may lead to diminished bony growth— vegetative mechanism of this, however, has not yet beenelucidated. The action of thymus on thyroid is far from clear, but the tendencyis to show a reciprocal checking action especially on the neuromuscularapparatus. The problem of myasthenia gravis has been thought tolie behind this reaction. The thyroids and parathyroids have distinctly different and even 170 THE ENDOCRINOPATHIES antagonistic activities: The former seems to be related more distinctlyto the iodine, the latter to the calcium metabolism of the body. Justhow they are regulated through the vegetative nervous system isunknown. Calcium-is of pronounced value in neuromuscular activity. Fig. 60.—To show the probable influence of the various endocrinous structures onone another. The following explanations apply to this and to the three succeeding figures. (Paton.) stimulation; inhibition. The arrow indicates the direction of action. Hyp., hypophysis; Par., parathyroid; Ch., Chromaffin system;Art., artery; Pit., pituitary; Thm., Thymus; Th., thyroid; G., glands; B., bone; In.,inter-renal; Pan., pancreas; M., muscle. (Paton.) as the phenomena of tetany show. Myasthenic states in general andmyasthenia gravis in particular are more directly related to disorderedthyroid and thymus activities. Lundborg has shown that the para-thyroid function plays some part in the reaction. The thyroid acts on the pancreas chiefly through its action on theliver sympathetic fibers. Sugar mobilization and release are brought
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