Human physiology . ghly alkalineurine (without either albuniinuria or glycosuria), hypothermia,rapid and progressive emaciation, coma not infrequently precedingdeath, which occurs in 2-11 days after the operation. Gatta (1896) and Kreidl and Biedl (1897) repeated theseexperiments, and obtained results which agreed approximatelywith those of Vassale and Sacchi. The syndrome obtained by Caselli (1900) in his many experi-ments on hypophysectomy in both dogs and cats was somewhatdifferent: depression of mental powers, motor disturbances,curvature of back, spastic gait without convulsions, progress


Human physiology . ghly alkalineurine (without either albuniinuria or glycosuria), hypothermia,rapid and progressive emaciation, coma not infrequently precedingdeath, which occurs in 2-11 days after the operation. Gatta (1896) and Kreidl and Biedl (1897) repeated theseexperiments, and obtained results which agreed approximatelywith those of Vassale and Sacchi. The syndrome obtained by Caselli (1900) in his many experi-ments on hypophysectomy in both dogs and cats was somewhatdifferent: depression of mental powers, motor disturbances,curvature of back, spastic gait without convulsions, progressivecachexia, rapid loss of weight, coma, death. This syndrome has undeniable resemblances with that whichappears after excision of the thyro-parathyroid organs, justifyingthe surmise of Rogowitsch (1888) that the pituitary and thethyroid glands are homologous, and are therefore able to functionvicariously. In order to discover why rabbits always supportthyroidectomy without injury, he made a microscopic examination. pil Weigerts method. (Lothringer.) The lighter, ]>rinci)julcells can be distinguished from the darker, chromaphilecells. 40 PHYSIOLOGY CHAP. of the various organs of these animals in search of possiblemodifications. The glandular part of the hypophysis proved tobe considerably larger in volume, with bigger follicles, and morecolloidal substance in the interfollicular spaces. This led him toconclude that in rabbits the hypophysis might supplement thyroiddeficiency. The experiments of Eogowitsch were repeated and confirmedby Stieda (1890), Hofmeister (1882), Gley (1892), and others. Tizzoni and Centanni (1890) observed the same facts in threedogs that long survived total thyroidectomy as Eogowitsch hadnoted on rabbits, and came to a similar conclusion. Schdueiuann(1892) adduced the results of clinical observation in support ofthe same thesis, and demonstrated a hypertrophy of the pituitarybody in cases of goitre, when a great part of the parenchyma ofthe thyroid gl


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectphysiology, bookyear1