. Animal parasites and human disease. Medical parasitology; Insects as carriers of disease. BARTONELLA BACILLIFORMIS 179 tion was favorable to recovery, a belief undoubtedly based upon the benign nature of verruga, leads to the adoption of all sorts of methods to invoke a breaking out of the skin, such as apphcations of turpentine, rubbing with irritant leaves, etc., and undoubtedly a great many cases of eruptions following Oroya fever are really only the eruptions caused by the artificial irritation of the skin. Oroya fever, after an incubation period of about 20 days, begins with a general f
. Animal parasites and human disease. Medical parasitology; Insects as carriers of disease. BARTONELLA BACILLIFORMIS 179 tion was favorable to recovery, a belief undoubtedly based upon the benign nature of verruga, leads to the adoption of all sorts of methods to invoke a breaking out of the skin, such as apphcations of turpentine, rubbing with irritant leaves, etc., and undoubtedly a great many cases of eruptions following Oroya fever are really only the eruptions caused by the artificial irritation of the skin. Oroya fever, after an incubation period of about 20 days, begins with a general feeling of malaise and aches in the joints, followed by chills and fever, which last irregularly for many weeks. The fever is accompanied by a rapid pernicious anemia, the red blood corpuscles being reduced in some cases to one-fifth, or even less, of their normal number. This causes severe prostration and in a large per cent of cases death results within three or four weeks. The skin assumes a yellowish waxy color, and there are often slight hemorrhages of the mucous membranes and various internal organs, as demonstrated by post mortem examinations. The liver and spleen become moderately enlarged, and the lymph glands are swollen. The Parasite. — The true parasite of Oroya fever was first discovered by Barton, of Lima, Peru, in 1905 and confirmed by him in 1909, at which time he suspected that it might be a protozoan. The parasites were more thoroughly studied by the Harvard expedition in 1913 and 1914 and named Barton- ella badlliformis. Dr. Strong and his colleagues describe them as minute rods or, more rarely, rounded bodies occur- ring inside the red blood cor- puscles (Figs. 54 and 55). These parasites, the rod form shaped individuals. , . ; 1 1 ir i o c Strong et al.) of which are only to m (less than —L__ of an inch) in length and the round bodies to 1 /x in diameter, are definitely motile, moving about freely inside the corpuscles. In severe infections t
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