. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. PHARMACOLOGY OF BUSYCON 475 LU (f) O O oi 100 75 50 -- 10 -11 10 -10 10'9 10'8 ID'7 MOLAR CONCENTRATION 10 -6 10 -5 LlJ (S) < -25 LlJ a: o Ld a -50 h- LJ o -75 LU a. -100. MCH 10 '9 10' 10 '7 10 '6 10 '5 10 '4 10 -3 MOLAR CONCENTRATION FIGURE 3. A. The effect of 5-hydroxytryptamine on the amplitude of beat of the isolated ventricles of Strombus f/ifias (solid line) and Aplysia protect, (broken line). B. The effects of acetylcholine, carbamylcholine, and acetylbetamethyl choline, on the amplitude of beat, of the Strombus g
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. PHARMACOLOGY OF BUSYCON 475 LU (f) O O oi 100 75 50 -- 10 -11 10 -10 10'9 10'8 ID'7 MOLAR CONCENTRATION 10 -6 10 -5 LlJ (S) < -25 LlJ a: o Ld a -50 h- LJ o -75 LU a. -100. MCH 10 '9 10' 10 '7 10 '6 10 '5 10 '4 10 -3 MOLAR CONCENTRATION FIGURE 3. A. The effect of 5-hydroxytryptamine on the amplitude of beat of the isolated ventricles of Strombus f/ifias (solid line) and Aplysia protect, (broken line). B. The effects of acetylcholine, carbamylcholine, and acetylbetamethyl choline, on the amplitude of beat, of the Strombus gigas ventricle, which is maintained by perfusion with 10~7 molar 5-hydroxytryptamine. myogenic pacemakers. A myogenic origin for the beat of the heart of trunciilns was indicated when Cardot, Jullien and Morin (1929) showed that isolated fragments would beat in sea water. Thus, the Busycon ventricle reacts to acetylcholine like the hearts of other gastropods which have been demonstrated to have myogenic pacemakers. The extremely low concentrations at which acetylcholine and 5-hydroxy- tryptamine are effective on the B-nsycon ventricle are in accordance with Welsh's (1957) rinding that they act as neurohumors in Venus uierccnaria. That 5- hydroxytryptamine is effective in lower concentration than adrenalin or noradren- alin. with an equally rapid onset of action, suggests that 5-hydroxytryptamine might. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983. Woods Hole, Mass. : Marine Biological Laboratory
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
