Gynaecology for students and practitioners . eposit of red necrosis, or necrobiosis as it is called, therewill be no fat. It may be concluded that the majority of cysts found in myomataare pseudo-cysts derived from liquefaction of hyaline deposit. Truecysts do exist in fibroids, and these will be referred to under Lyrnph-angiectasis. Fatty Degeneration. This change is far less commonly observedthan is hyaline degeneration. It is an essential precursor to calcareousdeposition, which is not an infrequent change, especially in fibroidsfound in elderly subjects. The probability, therefore, is that
Gynaecology for students and practitioners . eposit of red necrosis, or necrobiosis as it is called, therewill be no fat. It may be concluded that the majority of cysts found in myomataare pseudo-cysts derived from liquefaction of hyaline deposit. Truecysts do exist in fibroids, and these will be referred to under Lyrnph-angiectasis. Fatty Degeneration. This change is far less commonly observedthan is hyaline degeneration. It is an essential precursor to calcareousdeposition, which is not an infrequent change, especially in fibroidsfound in elderly subjects. The probability, therefore, is that fatty 448 GYNECOLOGY degeneration has often in the past escaped detection for want of suit-able staining reagents. For the study of the fatty stage in the degenera-tion of myomata, the fresh tissue should be taken, frozen sections made,and stained with Sudan III. The section is then mounted in Farrantssolution. The fat-droplets are picked out as deep orange or sunset-redglobules. They lie inside the muscle-fibres and therefore are arranged. ?^ Small degenerai-ioncysts Large cystic cavitybeneath capsule Fig. 224. Large Retroperitoneal Fibroid Tumour. A large subcapsularcystic space has been formed in the lower part of the Figure, and manysmaller spaces in other parts. The large cystic space has smooth walls, cf. Fig. 225. in the direction of the muscular bundles. The macroscopic appearanceof fat in a myoma is variable, being influenced by associated conditionsdue to changes in the blood. The cut surface of a fatty myoma maybe pale yellowish in colour, but it is often tinted by soluble blood-pigment. The normal whorled appearance is obscured, and thesurface is homogeneous. Microscopically, the changes are those of hyaline degeneration towhich the deposition of fat-globules is added. Thus there are seen(1) irregular and scanty nuclear staining ; (2) granular and hyalinechange ; (3) fat-globules running in the original direction of the SECONDARY CHANGES IN FIBROIDS 449 muscle-fibr
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectgynecology, bookyear1
