Formation of vessels in a blood clot. Light micrograph showing new vessels (small oval white spaces) in an old established blood clot (thrombus, light
Formation of vessels in a blood clot. Light micrograph showing new vessels (small oval white spaces) in an old established blood clot (thrombus, light pink, centre) that is blocking an artery (dark pink ring). Over time, granulation tissue gradually builds up in a thrombus. This eventually results in replacement of the thrombus by fibrovascular granulation tissue, as seen here. In some cases, larger vessels develop within this tissue. These vessels may allow blood to flow through the previously blocked area and may with time acquire smooth muscle walls. This is known as recanalisation.
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Photo credit: © BIOPHOTO ASSOCIATES/SCIENCE PHOTO LIBRARY / Alamy / Afripics
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