. Radiotherapy and phototherapy : including radium and high-frequency currents, their medical and surgical applications in diagnosis and treatment ; for students and practitioners . the epithelioma are seen inthe cutis vera and some of them present carious appearances;while some have typical nests of horny cells, in others thecentres have become disintegrated and are full of granulardebris, while others have tubes in them with well-definedwalls. Some of the conditions resembled those found inblastomycetic dermatitis, but special staining failed to showany of the blastomycetes. The above condit


. Radiotherapy and phototherapy : including radium and high-frequency currents, their medical and surgical applications in diagnosis and treatment ; for students and practitioners . the epithelioma are seen inthe cutis vera and some of them present carious appearances;while some have typical nests of horny cells, in others thecentres have become disintegrated and are full of granulardebris, while others have tubes in them with well-definedwalls. Some of the conditions resembled those found inblastomycetic dermatitis, but special staining failed to showany of the blastomycetes. The above conditions are seenin Figs. 83 and 84. Another marked change is found in the cutis vera whichis an alteration in the chemical reaction of some part of thewhite fibrous tissue and an alteration in its structure. A band of tissue is seen which has taken the logwoodstain in a different manner to the rest of the tissue. Thisband is seen to begin at the floor of the ulcer and to extend 360 RADIOTHERAPY under the intact epithelium for the whole length of thesection. It occupies the deeper part of the superficial cutisvera, that is, dividing the normal cutis vera into two parts, Fig. Varneys case. HISTOLOGICAL CHANGES CAUSED BY THE X-RAY 361 the superficial consisting of felted fibrous tissue on whichthe epidermis rests, and through which the ducts of the sweatglands pass. There is a layer of the superficial cutis directlyunder the epidermis which is entirely unaffected. Thechanged portion consists of altered fibrous tissue which hasstained a different color to the adjoining normal fibroustissue. A high magnification shows this altered tissue as amass of fibrils which in many places resemble long threads;with these fibrils are amorphous, irregularly shaped portionsof probably disintegrated white fibrous tissue and numerousdeeply stained nuclei of connective-tissue corpuscles. Thesealtered fibres occupy a distinct layer of the superficial cutisand are differentiated by the peculiar colo


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