Physiology and biochemistry in modern medicine . Fig. 191.—Tracing showing the effect of epinephrine on the intestinal contractions and on thearterial blood pressure. (The preliminary addition of barium to the nutritive fluid may be disre-garded.) (From Jackson.) small hook and above to a light muscle lever, by which the contractionof the muscle fibers can be observed. Epinephrine causes the muscle tocontract, but the test is not so sensitive as the foregoing, especially inthe presence of blood serum, because the pressor substances therein con-tained also cause contraction. Blood plasma does n
Physiology and biochemistry in modern medicine . Fig. 191.—Tracing showing the effect of epinephrine on the intestinal contractions and on thearterial blood pressure. (The preliminary addition of barium to the nutritive fluid may be disre-garded.) (From Jackson.) small hook and above to a light muscle lever, by which the contractionof the muscle fibers can be observed. Epinephrine causes the muscle tocontract, but the test is not so sensitive as the foregoing, especially inthe presence of blood serum, because the pressor substances therein con-tained also cause contraction. Blood plasma does not contain the pres-sor substances, so that oxalated plasma should be used in place of serum 742 THE ENDOCRINE ORGANS, OR DUCTLESS GLANDS in applying the test. To increase the sensitiveness of the muscle, theartery ring should be slightly stretched by loading the The blood vessels of a fro</. This method depends on the same prin-. Fig. 192.—Arrangement of apparatus for perfusion of the vessels of a brainless frog. (From Jackson.) ciple as in that just described. The fluid supposed to contain epinephrineis added to Lockes solution, which is meanwhile being perfused underconstant pressure through the blood vessels and the rate of outflow THE ADRENAL GLANDS 743 noted (Fig. 192). If the fluid added to the inflowing fluid contains epi-nephrine, the outflow will become diminished. This is a very satisfactorymethod, although it is somewhat limited in scope unless large frogs areprocurable, because of the difficulty of getting the necessary cannula?into the vessels (aorta and abdominal vein). 5. The pupil of the enucleated eye of the frog. Extremely small tracesof epinephrine are observed to cause a dilatation. 6. The denervated iris. The fluid to be tested is placed in the conjunc-tival sac of an animal from which the superior cervical ganglion of thecorresponding side has been removed some days previously. Under su
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