. A treatise on mental diseases. nite or anastomose in any way withany other of the vast myriads of neurones in the nervous system.* * The recent work of Apathy, who thought he observed the passage of the fibril-lie of one nerve cell into the protoplasm of other ganglion cells, and the researches1 Held, who advocates a subdivision of the ultimate axis fibrils within the body ofthe nerve cell, have not been confirmed by other observers; while the evidence ofthe silver method, which is clear and distinct in all details, tends to prove conclu-sively that such views are incorrect, at least for the


. A treatise on mental diseases. nite or anastomose in any way withany other of the vast myriads of neurones in the nervous system.* * The recent work of Apathy, who thought he observed the passage of the fibril-lie of one nerve cell into the protoplasm of other ganglion cells, and the researches1 Held, who advocates a subdivision of the ultimate axis fibrils within the body ofthe nerve cell, have not been confirmed by other observers; while the evidence ofthe silver method, which is clear and distinct in all details, tends to prove conclu-sively that such views are incorrect, at least for the higher vertebrates, and that therelation of cell to cell is by contiguity, each neurone being separate and distinct. Seealso the recent articles of Lenhossek in the Neurol. Centralblatt, Nos. 6 and 7, 1809. HISTOLOGY OF THE CORTEX 21 What is, then, the connecting link by which impulses may be trans-mitted from cell to cell to form waves of impulse, resulting in mo-tion ? It is supplied, as is shown by the very positive pictures. Fig. 5.—1, Psychical Neuhone, showing the end apparatus of a collateral situated againstthe dendrite of another cell. Drawn from a human specimen. 2, Forms of termina-tion of the ascending rihres of the cortex. Guinea-pig. obtained by silver staining, by the contiguity of the protoplasm ofthe distal extremity of the axone to the protoplasm of the extensions(gemmulae) of the dendrites of the cell body (Fig. 5). Such an 22 A TREATISE ON MENTAL DISEASES arrangement is very frequently seen within the cortex, where theterminations of the celJulipetal fibres, in the form of bulbar enlarge-ments, seek close approximation to the substance of the terminalknobs of the gemmules upon the dendrites. This method of ter-mination does not preclude the possible existence of subsidiaryones, but it is certainly the chief and most important. Direct contact seems to be avoided by the interposition of aninfinitesimal space between the two free endings. Contact betweenthe


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