. A practical treatise on tumors of the mammary gland: . rs of other organs, so that the large, refractory,vesicular cells and the lamination are the most char-acteristic features of the neoplasm. In some cases,indeed, the cells were only the seat of fatty degenera-tion. 4. Melanotic, or Pigmented, Carcinoma is char-acterized by the infiltration of the cells with granulesof melanin or altered hematoidin. 5. Cystic Carcinoma.—It sometimes happens thatthe obstructed and dilated terminal acini and ductsof mammae which are the seat of cancer are convertedinto cysts through mucoid or fatty transfor


. A practical treatise on tumors of the mammary gland: . rs of other organs, so that the large, refractory,vesicular cells and the lamination are the most char-acteristic features of the neoplasm. In some cases,indeed, the cells were only the seat of fatty degenera-tion. 4. Melanotic, or Pigmented, Carcinoma is char-acterized by the infiltration of the cells with granulesof melanin or altered hematoidin. 5. Cystic Carcinoma.—It sometimes happens thatthe obstructed and dilated terminal acini and ductsof mammae which are the seat of cancer are convertedinto cysts through mucoid or fatty transformation oftheir epithelium. In addition to these simple reten-tion or involution cysts, that are combined with, al-though they precede the development of, carcinoma^ CARCINOMA. 137 cysts are sometimes met with, as iu fig. 25, whichare more or less completely filled with vascular, epi-thelial-clad vegetations, or papillae, which are merelyprotrusions of the periacinous connective tissue intotheir interior, and are themselves devoid of carcino- FiG. Cystic Encephaloid Carcinoma.—Showing, in addition to simple cysts, twocavities occupied by vegetations. matous structure. Cornil and Ranvier^ describe thisproliferating form as villous carcinoma; while Neu-mann terms the case which he records encystedmedullary carcinoma. It is not, however, peculiar tosoft carcinoma, as a specimen of scirrhus in the col-lection of Professor Gross shows a similar combina-tion ; and Mr. Wood * reports an example of hard car-cinoma of the male mamma in which the papillae wereso vascular as to convert the cavities containing theminto blood cysts. In addition to the preceding varieties, we mayhave a myxomatous cancer through mucous transfor-mation of the stroma, or a calcifying cancer through * From a medullary carcinoma, devoid of history, from the cabinet of Pro-fessor Gross. Op. ciL, p. 1167. Virchows Archiv, Bd. xxiv, p. 319. * Trans. Path. Soc. London, vol. xxv, p. 223. 138 VARIETIES. the dep


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