Archives of internal medicine . presenl available seem to indicate thai the effecl on the offspring isequally ac greal when it is produced by an alcoholic father as by analcoholic mol There are only four matings between alcoholized females and normalmales. One of these gave a negative resull or Was possibiy aborted veryearly. Three living litters were born. One of these consisted of three CHARLES K. 8T0CKARD 391 premature young, which died shortly after birth. The remaining twolitters each contained only one young, but these two animals of tbese guinea-pigs was born after tbe moth
Archives of internal medicine . presenl available seem to indicate thai the effecl on the offspring isequally ac greal when it is produced by an alcoholic father as by analcoholic mol There are only four matings between alcoholized females and normalmales. One of these gave a negative resull or Was possibiy aborted veryearly. Three living litters were born. One of these consisted of three CHARLES K. 8T0CKARD 391 premature young, which died shortly after birth. The remaining twolitters each contained only one young, but these two animals of tbese guinea-pigs was born after tbe mother had been treated forthree and one-half months. The offspring was weak and small for severalmonths after birth, but finally recovered and developed into a normalanimal. This guinea-pig was mated with an alcoholic male and becamepregnant. Unfortunately, she was killed by accident, and on examina-tion her uterus was found to contain two embryos, 33 and 32 mm. inlength. One of these embryos was deformed and showed very decidedly. Fig. 3.—Two embryos 32 and 33 mm. in length, taken from a female that hadan alcoholic mother and was mated with alcoholic male. The upper fetus hasdeformed hind legs and a poorly developed posterior part of the body; lower fetusis normal. degenerate and feebly developed hind legs. The posterior end of its bodywas also poorly formed. This condition is readily seen in Figure 3, aphotograph of the two embryos. The abnormal one has small hind legs,and one of them is badly folded under its body. This is of interest, sinceall of the affected offspring of alcoholic guinea-pigs are weak in theirhind extremities and drag their legs. Yet none were so modified as toshow a noticeable structural defect except this embryo, which had onealcoholic grandmother and an alcoholic father. 392 IRCH1VE8 OF IXTERXAL //:///7 \/•: The only other survivor from an alcoholic mother is strong and fullgrown for its age. The mother had been treated for only two and <»n<-hal
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