Elements of pathological anatomy . ll be in addition,especially in young subjects, a partial sepa-ration of the cellulo-fibrous lamella and of themuscular fibres. These effects I have repeat-edly witnessed in my experiments on dogs, andthey may be readily produced in the humanbody after death. If a flat ligature be used,even when it is drawn with considerable firm-ness, the opposite surfaces of the tube aremerely brought into contact, without anyrupture of the substance of any of thetunics. The only exception to this is wherethe animal is very young and the parietes ofthe bowel are unusually t


Elements of pathological anatomy . ll be in addition,especially in young subjects, a partial sepa-ration of the cellulo-fibrous lamella and of themuscular fibres. These effects I have repeat-edly witnessed in my experiments on dogs, andthey may be readily produced in the humanbody after death. If a flat ligature be used,even when it is drawn with considerable firm-ness, the opposite surfaces of the tube aremerely brought into contact, without anyrupture of the substance of any of thetunics. The only exception to this is wherethe animal is very young and the parietes ofthe bowel are unusually tender; in whichcase there will be occasionally a slight divisionof the lining membrane, but not of the mus-cular fibres. When a narrow ligature is used,the parts above and below it are so closelyapproximated that they touch in the greaterportion of their circumference; a circumstance which must necessarily exert a * See my Experimental and Critical Inquiry into the Nature and Treatment of Wounds of theIntestines. Louisville, WOUNDS. 603 most favorable influence over the reparative process and the re-establishmentof the continuity of the canal. Soon after an operation of this kind, in which a narrow circular ligatureis used, inflammation is set up, plastic lymph is deposited upon and around theconstricted parts, ulcerative absorption is established, and the cord at lengthworks its way into the intestinal tube, where it is discharged along with thefaeces. The period required for the detachment of the ligature may be sup-posed to be influenced by various circumstances, the principal of which arereferable to the form and size of the foreign substance, together with the forcewith which it is applied, the thickness of the different tunics of the bowel,the age of the subject, and the state of the general health at the time ofthe operation, as well as immediately after it. In a small but full grown dog,killed at the end of the third day after the experiment, the ligature, which


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