. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). ent only inmoderate intensity in the tibialis anticus muscle. Lumbar and Sacral Ganglia.—The cells of the capsules aremuch proliferated, many of the nerve cells are much shrunken,and many are highly pigmented. With thionin many of the nervecells are pale and have peripheral nuclei. Medullated fibers are 420 iriLLIAM G. SPILLER not very numerous within the ganglia, but are equally numerousat the two ends of a ganglion. A radicular nerve from a lowerganglion shows slight cellular infiltration. Gasse
. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). ent only inmoderate intensity in the tibialis anticus muscle. Lumbar and Sacral Ganglia.—The cells of the capsules aremuch proliferated, many of the nerve cells are much shrunken,and many are highly pigmented. With thionin many of the nervecells are pale and have peripheral nuclei. Medullated fibers are 420 iriLLIAM G. SPILLER not very numerous within the ganglia, but are equally numerousat the two ends of a ganglion. A radicular nerve from a lowerganglion shows slight cellular infiltration. Gasserian Ganglion.—Some proliferation of the cells of thecapsules is found but not so much as in the lower spinal is a distinct increase of round cells between the nerve nerve cells are not much altered except that some are muchpigmented. The sensory roots of both fifth nerves are muchdegenerated. Some bundles are deeply stained by the Weigertmethod, and these probably belong to the motor portion. Thespinal roots in the medulla oblongata, however, show Fig. 8. Section from the extensor communis digitorum muscle,,stained Ijy the Marchi method. Numerous small black dots, caused byfat withinthe muscle fibers, are seen. The medulla oblongata shows no degeneration of the anteriorpyramids. The cells of the lower olive are normal in numberbut are much smaller. The optic nerves and chiasm are notdegenerated. I am indebted for the photographs illustrating this case to J. Smith. The following clinical case of Friedreichs ataxia has beenin my service frequently at the Philadelphia General Hospital,and has been studied also by my colleagues on the neurologicalstaff. It is included because of the pronounced atrophy of thelimbs. FRIEDREICHS ATAXIA 421 W. Soudan, 41 years old, began to walk when three years old,and walked with a cane until he was 15 years old. He staggeredmuch and was clumsy in lifting his feet, and often fell whenwalking. In
Size: 1579px × 1583px
Photo credit: © Reading Room 2020 / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1900, bookidcontribution, bookyear1906
