Gynaecology for students and practitioners . muscle may take part in a malignant metaplasiasimultaneously. On the other hand, it has been proved that the changemay arise in the muscle-tissue only {see Figs. 227 and 228). Sar-comatous metaplasia of muscle leads to a fibrosarcoma, that is, thereis a preponderance of spindle cells and cells with processes {see Fig. 228);the round cells of lower type seen in malignant metaplasia of connec-tive tissue are less in evidence or altogether absent. Attention has MALIGNANT CHANGES IN FIBROIDS 457 already been drawn to the close association of hyaline deg


Gynaecology for students and practitioners . muscle may take part in a malignant metaplasiasimultaneously. On the other hand, it has been proved that the changemay arise in the muscle-tissue only {see Figs. 227 and 228). Sar-comatous metaplasia of muscle leads to a fibrosarcoma, that is, thereis a preponderance of spindle cells and cells with processes {see Fig. 228);the round cells of lower type seen in malignant metaplasia of connec-tive tissue are less in evidence or altogether absent. Attention has MALIGNANT CHANGES IN FIBROIDS 457 already been drawn to the close association of hyaline degeneration ofconnective tissue and malignant metaplasia of muscle. Fibromyomata of the uterus are sometimes invaded by a sarcomaarising in the uterine wall {see Figs. 229 and 230), and it is due to thisfact that doubt has arisen as to a true malignant change arising denovo in the fibromyomatous tissue itself. A sarcoma starting in the muscle-wall of the uterus is difficult todistinguish from one starting in the muscle of a fibroid tumour, as.


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectgynecology, bookyear1