Handbook of meat inspection . satisfactory. 01t demonstrated, in tbe first place,tbat granulär eruption is a skin disease of progressive cbaracter;tbat tbe diseased parts of tbe skin are sbarply delimited, andexbibit large cysts in tbe middle and smaller ones at tbe formed tubercles, recognizable by tbe naked eye, are ofminute size, pale-yellow, or often almost wbite. By furtber growthin a superficial position, tbe tubercles acquire tbe sbeeu of duU GENERAL INTEGUMENT 271 pearls. Later, thoj ])ec()me nisset-iecl, yellowisb-brown to brown,aiul finallj blue-black, with a metal
Handbook of meat inspection . satisfactory. 01t demonstrated, in tbe first place,tbat granulär eruption is a skin disease of progressive cbaracter;tbat tbe diseased parts of tbe skin are sbarply delimited, andexbibit large cysts in tbe middle and smaller ones at tbe formed tubercles, recognizable by tbe naked eye, are ofminute size, pale-yellow, or often almost wbite. By furtber growthin a superficial position, tbe tubercles acquire tbe sbeeu of duU GENERAL INTEGUMENT 271 pearls. Later, thoj ])ec()me nisset-iecl, yellowisb-brown to brown,aiul finallj blue-black, with a metallic luster. The largest vesicles Ft.:. I!I. K \ {{ 1;: (j > Vk> ^^, ^•^^ A V ^V -•r r % \- 4,** •?> ~*- -Ü i* ? i:-^?^ - ®5 . :\ Granulär eruption of the hog after reraoval of the normal bristlos. In some of thetubercles coileu and protruding bristles are seeu. are of the size of mustard seeds, or, rarely, as large as peas. Thevesicles are filled with a cloudj, watery fluid, and usually coutain Fig. Granulär eruption of the hof^. Cross-section of a convoluted gland (after 01t)«, coccidia surrounded with shells and lying between the disinfegrated epiLbelia. one, or, according to circumstances, two or three, rarely more,bristles. Furthermore, 01t discovered from serial sections that thepathological process arises iu the sweat glauds, aud is caused by 272 NOTEWORTHY ORGANIC DISEASES coccidia, whicli are- parasitic in tlie epithelia of tlie sweat glancls^and cause a proliferation of tlie epithelial layer {spiradenitis coccid-^iosa). The epithelial proliferation leads to inhibition of the secretionand to the formation of a cyst. The bristles come to lie in the cysts»either throngh fusion of the hair follicles with the cysts, or byPenetration of developing bristles into the primary cysts of theconvoluted glands. The fuUy developed coccidia have a membrane,are ovate, .034 mm. long, .0275 mm. wide, and, therefore, somewhafcthicker than Coccidium ovi/orme (Fig
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