. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 2s DILL, EDWARDS AND FLORKIX that the environment of hemoglobin is very different in these cases. It will be recalled that an abnormal value for a similar relationship was found in man in diabetic coma (Dill and others, 1929). Further di><-ussion of this question had better wait, therefore, until it is possible to prepare these hemoglobins in the pure state and study them under strictly comparable conditions. The data given in Table II have been used to construct the oxygen dissociation curves of Fig. 4. These have bee
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 2s DILL, EDWARDS AND FLORKIX that the environment of hemoglobin is very different in these cases. It will be recalled that an abnormal value for a similar relationship was found in man in diabetic coma (Dill and others, 1929). Further di><-ussion of this question had better wait, therefore, until it is possible to prepare these hemoglobins in the pure state and study them under strictly comparable conditions. The data given in Table II have been used to construct the oxygen dissociation curves of Fig. 4. These have been drawn as members of the same family of curves, and aside from a few bad results the fit accords with this assumption. The effect of temperature on the affinity of blood for oxygen has been shown graphically for human blood by Brown and Hill (1923). Use has been made of their data and that of Fig. 4 in Fig. 5. This comparison indicates that q, the heat of reaction of 1 gram molecule of hemoglobin with ;/ gram mole-. 60 80 100 120 140 160 p02 in ISO 200 220 Z40 260 1;1G. 4. Oxygen <li-s('d, =-- 1 ± mm. rules of oxygen, is the same for the blood of the skate and of man. The significance of n remains somewhat obscure, but it is useful in characteri/ing the slope of the oxygen dissociation curve when log p().j = I log Hb'HbO-j. It has the value of in man and in skate's blood it is slightly smaller, i'iz., If we accept the definition ..I ;/ ui\en by Hrown and Hill, it follows that the value for (J, the heat evoKfd \\lirn 1 grain molecule of oxygen combines at constant \olume with hemoglobin, is about the same as in human blood. ( MM- miM have a description of the carbonic arid dissociation curve of blood in order to understand the conditions under which carbon dioxid- is excreted through the gills. It is known from the work of Collip (1920), confirmed by others (Kokubo, 1927 and Smith, \(>2{>t. that the carbonic acid content of selachian blood is no mo
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