This image of a breast cancer tumor and its microenvironment was obtained from a live mouse model using multiphoton microscopy and endogenous fluorescence. That is, the image was obtained without fluorophores, stains or dyes, using only the metabolic cofactors of NADH and FAD, which are already inside the cells, as well as second harmonic generation to see the collagen. This technique has significant clinical potential for patients who need label-free imaging and can lead to more effective diagnoses and treatments.

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Photo credit: © NIH / IMAGE POINT FR / BSIP / Alamy / Afripics
License: Licensed
Model Released: No

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