Organic and functional nervous diseases; a text-book of neurology . long duration, reliable ob-servers have reported secondary degenerations in both sensory andmotor tracts, but those are certainly the exception. The essential feature of the disease is therefore the production of a 678 MULTIPLE SCLEROSIS. peculiar neuroglia structure which is associated with a disappearanceof the myelin sheaths of nerve fibres. There are many theories inregard to this process, no one of which is generally accepted. Striimpellbelieves that it is a congeuitah affection of the nature of gliosis, notunlike syringo
Organic and functional nervous diseases; a text-book of neurology . long duration, reliable ob-servers have reported secondary degenerations in both sensory andmotor tracts, but those are certainly the exception. The essential feature of the disease is therefore the production of a 678 MULTIPLE SCLEROSIS. peculiar neuroglia structure which is associated with a disappearanceof the myelin sheaths of nerve fibres. There are many theories inregard to this process, no one of which is generally accepted. Striimpellbelieves that it is a congeuitah affection of the nature of gliosis, notunlike syringomyelia {q. v.), and that the nerve fibres are affectedsecondarily. He urges as proof the fact that it occurs in suggests that instead of a process of degeneration of themyelin sheath there has been a defective development of myelin origi-nally, and that the naked fibres have never developed a myelin cover-ing, a possibility which is rendered more likely because of the fact thatin the development of the nerve fibres the myelin appears later than. the axone. Under these conditions it would be expected that thesymptoms would appear in infancy instead of developing after the ageof ten years or later. Rindfleisch and others, Ribbert, Fiirstner, Marie, Bartsch, andSchmaus believe that the process is vascular in origin, a toxic agentia the blood affecting first the vessels, then the medullary sheath of ETIOLOGY. 679 the nefves, and then leading to a secondary sclerosis. They affirmthat the j^laques lie about the vessels, which others deny. Othersaffirm that a lymph stasis in the lymph spaces about the bloodvesselsis the primary cause; that these spaces are crowded with epithelioidcells which distend them, hinder the flow of lymph, and thus lead toswelling and degeneration of the glia cells and nerve elements, andfinally to a sclerosis. But this theory has met with little favor, as themajority of observers regard this lymph stasis as a result and not as acause, and wh
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectnervoussystem, bookye
