Medical and surgical reports . that in pernicious anemia the count rises temporarily, and then fallsrapidly to the previous level or below. The transfused blood is rapidlydestroyed in these cases. Phagocytosis in the blood-destroying organsis usually performed by macrophages, but in this case the polynuclearsmay have taken part in the process and then have been washed intothe circulation. The phagocytosis might also be accounted for by the presence of anopsonin for human red blood cells. Savtchenko9 found that theinjection of inactivated serum of a rabbit immune to guinea-pig cor-puscles, toge
Medical and surgical reports . that in pernicious anemia the count rises temporarily, and then fallsrapidly to the previous level or below. The transfused blood is rapidlydestroyed in these cases. Phagocytosis in the blood-destroying organsis usually performed by macrophages, but in this case the polynuclearsmay have taken part in the process and then have been washed intothe circulation. The phagocytosis might also be accounted for by the presence of anopsonin for human red blood cells. Savtchenko9 found that theinjection of inactivated serum of a rabbit immune to guinea-pig cor-puscles, together with guinea-pig corpuscles, into the peritoneum of aguinea-pig, was followed not always by hemolysis, but sometimes byphagocytosis. Levaditi10 found some phagocytes containing red cellsin the circulating blood and great numbers in the spleen, after suchinjections. They attributed this action to the same substance sensi-bilisatrice (fixateur) that caused hemolysis, acting in this case in theabsence of free cytase (alexin).. Fig. 4.— Phagocyte with one red cell, show- Fig. 5.—Phagocyte with two red cells, show- ing polymorphous nucleus. Wood stain; X ing neutrophil granulation. (Jenner stain:1,000) X 1,000.)
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Keywords: ., bookcentury1900, bookdecade1900, bookpublisherchica, bookyear1904
