Archives of internal medicine . Shott Serum incubation disease Fig. 5.—Accelerated serum disease. lost the precipitin in its blood. We see here that the antibody appearsas early as the sixth day, and consequently the horse-serum disappears atthe same time. This is the accelerated reaction. In rabbits, however,we are not able to observe the clinical phenomena seen in man, indicatedby the lower part of the figure. The serum disease appears after an incu-bation time as short as five days. Figure 6 adds one more complication to the process. A man isinjected who had been injected before and who sti


Archives of internal medicine . Shott Serum incubation disease Fig. 5.—Accelerated serum disease. lost the precipitin in its blood. We see here that the antibody appearsas early as the sixth day, and consequently the horse-serum disappears atthe same time. This is the accelerated reaction. In rabbits, however,we are not able to observe the clinical phenomena seen in man, indicatedby the lower part of the figure. The serum disease appears after an incu-bation time as short as five days. Figure 6 adds one more complication to the process. A man isinjected who had been injected before and who still contains horse-serum reacts first with the existing antibody. The toxicsubstance produced at that time causes an immediate reaction, but the C. E. VON PIRQUET HoYse*serum 413. Immediate ^ISllion*reaction Seturo disease Fig. 6.—Double reaction after reinjection in man. Days ? Hofse-serum .3Jnlectioo ? ? I ? ? .


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