. St. Louis courier of medicine. beautifully illustrated, while the printing and bindingare excellent. H. CURIER OF MEDICINE POCKET REFERENCE BOOKAND VISITING LIST. (Perpetual*. 1900. Handsomely anddurably bound in Red Morocco. Price, 75 as. [St. Louis : TheCourier of Medicine Co., Publishers.] It is as necessary for a physician to record his business as it is fora mercantile business to keep books. The essential book is a day-book in which business is recorded as it occurs. This is what a visitinglist purports to be. The Courier Visiting List is especially valuablebecause it is without dates.


. St. Louis courier of medicine. beautifully illustrated, while the printing and bindingare excellent. H. CURIER OF MEDICINE POCKET REFERENCE BOOKAND VISITING LIST. (Perpetual*. 1900. Handsomely anddurably bound in Red Morocco. Price, 75 as. [St. Louis : TheCourier of Medicine Co., Publishers.] It is as necessary for a physician to record his business as it is fora mercantile business to keep books. The essential book is a day-book in which business is recorded as it occurs. This is what a visitinglist purports to be. The Courier Visiting List is especially valuablebecause it is without dates. It is, consequently, perpetual, and can beused for an unlimited number of visits. As a visiting list is always athand, it can be made more ualuable by an addition of printed matterwhich can be readily referred to. The printed matter of the CourierVisiting List is abundant and well arranged, making the book of greatassistance in bedside study. The book is recommended by reason of its real value and great usefulness. M. —320—. SEE PAGE 378 ST. LOUIS COURIER OF MEDICINE Vol. XXI. NOVEMBER, 1899. No- 5- ORIGINAL CONTRIBUTIONS. Multiple Sclerosis. By PHILIP ZENNER, , , OF CINCINNATI, OHIO, LECTURER ON DISEASES OF THE NERVOUS SYSTEM IN THE MEDICAL DEPARTMENTOF THE CINCINNATI UNIVERSITY. MULTIPLE sclerosis, or cerebro-spinal sclerosis is, attimes, when presenting its most characteristic features,the most striking disease of the nervous system, andthe most easily recognized and, again, it is very obscure andalmost impossible of diagnosis. It presents usually many fociof disease ; these may be scattered over every part of thecentral nervous system and even involve the roots of thenerves. But they occur, as a rule, in certain parts ; in thewhite matter much more than in the gray, and chiefly in thepons, internal capsule, centrum ovale and the white columnsof the cord. The patches of the disease, rounded or irregularin outline, are of variable size, from l/s5 of an inch to 1


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Keywords: ., bookcentury1800, bookdecade1890, booksubjectmedicine, bookyear189