. Pathology and bacteriology [electronic resource]. Ophthalmology; Eye; Eye; Bacteriology; Ophthalmology; Eye; Bacteriology; Eye. WOUNDS OF THE CORNEA 373 2. Where a fold of iris prolapses through the whole thickness of the cornea. 3. Where a fold of iris prolapses between the posterior layers of the cornea only. I. The cut end of a piece of iris lying between the lips of a corneal wound causes more cell exudation and forma- tion of granulation tissue than in an uncomplicated wound. Fig. 201.—Section showing the prolapse of a knuckle of iris into a wound at ohe sclero-corneal margin. The eye h
. Pathology and bacteriology [electronic resource]. Ophthalmology; Eye; Eye; Bacteriology; Ophthalmology; Eye; Bacteriology; Eye. WOUNDS OF THE CORNEA 373 2. Where a fold of iris prolapses through the whole thickness of the cornea. 3. Where a fold of iris prolapses between the posterior layers of the cornea only. I. The cut end of a piece of iris lying between the lips of a corneal wound causes more cell exudation and forma- tion of granulation tissue than in an uncomplicated wound. Fig. 201.—Section showing the prolapse of a knuckle of iris into a wound at ohe sclero-corneal margin. The eye had had an iridectomy performed for glau- coma a fortnight previous to its removal. The prolapse was at one margin of the coloboma. It represents the first stage in the formation of a cystoid cicatrix. Ultimately the stroma of the entangled iris atrophies, its pigment epithelium remaining incorporated in the cicatricial tissue. 2. When a fold of iris prolapses through the whole thickness of the cornea an obstruction is imposed to the reunion of the fibrous tissue on the two sides (Fig. 201). A fibrinous exudate, which is afterward transformed into fibrous tissue, first agglutinates it to the sides of the wound, the stroma of the iris atrophies, and its pigment epithelium alone remains. A piece of iris left protruding through a wound develops granulation tissue on its surface. Over this granulation tissue the epithelium from the sides of the wound spreads, and it itself becomes transformed into fibrous tissue. If the wound is at the periphery of the cornea the prolapsed iris may be covered by conjunctiva to which it will become adherent. A permanent gap will then be left in the outer wall of the eyeball covered by conjunctiva and lined by the pigment epithelium of the iris; this as the result of intra-ocular tension will tend to stretch and expand, forming what is termed a cystoid cicatrix. As the scar stretches, gaps form in the continuity of the pigment epithelium lining it,
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