. Applied immunology : the practical application of sera and bacterins prophylactically, diagnostically, and therapeutically. rilythrust into the so-called negative phase. Thera-peutically, therefore, bacterin therapy is indicatedonly in chronic or possibly also subacute localized in-fections. It is impossible to conceive by any stretchof the imagination the rationale or at least the necessityof their employment in acute or diffused infectionsin which the human organism is already overloadedwith the products of a living antigen, or indeed itsdefences actually demolished and its system over-whe


. Applied immunology : the practical application of sera and bacterins prophylactically, diagnostically, and therapeutically. rilythrust into the so-called negative phase. Thera-peutically, therefore, bacterin therapy is indicatedonly in chronic or possibly also subacute localized in-fections. It is impossible to conceive by any stretchof the imagination the rationale or at least the necessityof their employment in acute or diffused infectionsin which the human organism is already overloadedwith the products of a living antigen, or indeed itsdefences actually demolished and its system over-whelmed by the invading microbes; namely, suchstates as bacteremia or septicemia. Indeed, bacterialinoculations in such conditions not only add insult toinjury but may be the determining forces for deathinstead of prolonged recovery. Administered in acutelocalized affections, as a rule unwisely perhaps, andcertainly so unless the indications of the opsonic indexare followed, either of two possible results may be ex-pected. If the bodily resources are barely able tocope with the situation, and the local infection be very ra.


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Keywords: ., bookcentury1900, bookdecade1910, bookpublisherphila, bookyear1916