Nervous and mental diseases . e excessive function of theglandular elements of this organ. The masterly studies, animal experi-ments, and operations of Cushing7 make it evident that excessive activ- 1 Franchini and Giglioli, JStouvelle Iconographie de la Salpetiere, Oct., 1908. 2 Jokoloff, Virchows Archiv, Bd. xliii. 3 Rev. Neurolog., Jan. 15, 1908. 4 Berlin, med. Woeh., 1900. 5 Virchows Archiv, vol. clxiv, 344. 6 il Johns Hopkins Hosp. Bull., Mar., 1908. 7 May, 1910. TROPHONEUROSES. 499 ity of the pituitary is associated with abnormally increased growth,under- or hypopituitary activity


Nervous and mental diseases . e excessive function of theglandular elements of this organ. The masterly studies, animal experi-ments, and operations of Cushing7 make it evident that excessive activ- 1 Franchini and Giglioli, JStouvelle Iconographie de la Salpetiere, Oct., 1908. 2 Jokoloff, Virchows Archiv, Bd. xliii. 3 Rev. Neurolog., Jan. 15, 1908. 4 Berlin, med. Woeh., 1900. 5 Virchows Archiv, vol. clxiv, 344. 6 il Johns Hopkins Hosp. Bull., Mar., 1908. 7 May, 1910. TROPHONEUROSES. 499 ity of the pituitary is associated with abnormally increased growth,under- or hypopituitary activity, with retarded growth, and both withgenital inactivity. It is also evident that there are functional linksbetween the pituitary, thymus, thyroid, and genital glands. Morbid Anatomy.—The bones of the face, cranium, extremities,and to a lesser degree those of the trunk, show hypertrophy. Thefrontal and occipital bones are commonly thickened and their markingsexaggerated. The frontal and maxillary sinuses are enlarged and the.


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