The effects of inanition and The effects of inanition and malnutrition upon growth and structure effectsofinaniti00jack Year: 1925 78 INANITION AND MALNUTRITION Reeb ('05) for rabbits and dogs. King ('15, '21) observed subnormal average weights of young albino rats born (sometimes stillborn) from mothers in ill- health, and ascribed the result to prenatal malnutrition. The extensive experiments of Barry ('20, '21) indicate that underfeeding of the pregnant albino rat must be severe in order to obtain positive results. When starvation is instituted shortly after copulation, pregnancy is interr
The effects of inanition and The effects of inanition and malnutrition upon growth and structure effectsofinaniti00jack Year: 1925 78 INANITION AND MALNUTRITION Reeb ('05) for rabbits and dogs. King ('15, '21) observed subnormal average weights of young albino rats born (sometimes stillborn) from mothers in ill- health, and ascribed the result to prenatal malnutrition. The extensive experiments of Barry ('20, '21) indicate that underfeeding of the pregnant albino rat must be severe in order to obtain positive results. When starvation is instituted shortly after copulation, pregnancy is interrupted by resorption of the ovum. If inanition is instituted in the second half of preg- nancy, death and degeneration of the fetus occur in a few cases. No abortions were observed (contrary to Diatschenko ('97, '99) and Reeb ('05) in rabbits) the pregnancies proceeding to full term, as was likewise observed by Paton ('03) and Rudolski ('05). Forty-one of 120 offspring were apparently stillborn, original body wciuHt ~~ \ ~~~~£- TE5TI5\ 2~ I I I I I I I I I I I I I I I I I I I II I I I I I I riNAL BODY — WEIGHT ~„ RICE. DICT— GOHtfige lil h N H H U nitiL ulii L U U U l\ IwliLili I I H M M M h'l M M M M M M M M W HVP0PH\3Ij> — 1 IB Fig. 35.—Diagram showing the relative degree of atrophy (change in weight) of the body and of various organs in pigeons during (i) total inanition and (2) partial inanition (milled rice diet, deficient in various respects). The loss in body weight is about 40 per cent in each case. There is a marked increase in weight of the suprarenals; the brain and hypophysis show little or no change; while the other organs show variable losses in weight. (From McCarrison '21; 'Studies in deficiency disease,' Oxford Med. Publ.; body weight corrected.) however, and the average weight of the newborn rats from these severely starved mothers was only about 3 g. or 40 per cent below the normal birth weight of 5 g. (see Table 4). Human Prenatal Inanitio
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