. A Reference handbook of the medical sciences : embracing the entire range of scientific and practical medicine and allied science. resent anotherfeature which is highly characteristic of them. Theydiffer from embolic areas in having a redder color, infact often appearing hyperaemic, whereas the embolicarea in its stage of contraction is strikingly surface of the cicatrix is quite uneven and irregular,and may by this means, if such distinction were evernecessary, be distinguished from the regular, coarse orfine, granulations of the surface of a contracting kidney. The contracting


. A Reference handbook of the medical sciences : embracing the entire range of scientific and practical medicine and allied science. resent anotherfeature which is highly characteristic of them. Theydiffer from embolic areas in having a redder color, infact often appearing hyperaemic, whereas the embolicarea in its stage of contraction is strikingly surface of the cicatrix is quite uneven and irregular,and may by this means, if such distinction were evernecessary, be distinguished from the regular, coarse orfine, granulations of the surface of a contracting kidney. The contracting kidney very constantly shows the smallislets of yellowish spots of fatty degeneration regularlyinterspersed through it, not only on the surface but inthe depth of the cortex. Such spots are never to be found in the syphiliticcicatrix, and this difference serves to point out, even inthe same kidney, the parts affected by the syphiliticcicatrization and those involved in the usual granularprocess of interstitial nephritis. Fig. 4124, taken from the kidney of the same case asthe preceding (half-inch objective), shows a portion of. Fig. 4124. the cortex immediately beneath the surface-depression ofa syphilitic cicatrix. In the upper part of the picture isseen the notch of the cicatrix, and over this surface thecapsule is increased to many times its normal thickness ;the capsular tissue, while showing some increase of itscoarse fibres, is mostly composed of pale-stained nucleiimbedded in a faintly fibrillar tissue. The appearancesrepresent to ones mind a falling in of the capsule ratherthan the forcible drawing-in such as occurs in intersti-tial nephritis, or after the organization of an embolic in-farct. The depression represents the seat of the innerhalf of the gumma, while the other half of the gummaoriginally projected above the level of the cortex. Thecortical tissue, under the depression, has apparently suf-fered mostly from the reactive inflammatory changeswhich always take p


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Keywords: ., bookcentury1800, bookdecade1880, booksubjectmedicine, bookyear188